Zubkiewicz-Kucharska Agnieszka, Noczyńska Anna, Sobieszczańska Małgorzata, Poręba Małgorzata, Chrzanowska Joanna, Poręba Rafał, Seifert Monika, Janocha Anna, Laszki-Szcząchor Krystyna
Department of Pediatric Endocrinology and Diabetology, Wrocław Medical University, Chałubińskiego Str. 2a, 50-368 Wrocław, Poland.
Department of Pediatric Endocrinology and Diabetology, Wrocław Medical University, Chałubińskiego Str. 2a, 50-368 Wrocław, Poland.
J Diabetes Complications. 2021 Nov;35(11):108043. doi: 10.1016/j.jdiacomp.2021.108043. Epub 2021 Sep 1.
Body Surface Potential Mapping (BSPM) is a multi-electrode synchronous method for examining electrocardiographic records on the patients' body surface that allows the assessment of changes in the heart conduction system. The aim of the study was to visualize and evaluate changes in the intraventricular system in adolescents with T1D.
Inclusion criteria: age > 12 years, T1D duration >3 years, HbA1c >8%.
diagnosis of autonomic neuropathy, heart structural defects, heart failure. BSPM data were processed into map plotting to illustrate differences in ventricular activation time (VAT, isochron lines).
33 teenagers (20 boys), mean age 15.0 ± 2.1 years, T1D from 6.8 ± 4.1 years were included. Mean HbA1c was 9.6 ± 2.0%. In the standard ECG recording abnormalities were not present. The distribution of isolines on the group-mean map plotted for T1D patients only initially resembles the course of isolines on the group-map for normal subjects (N = 30), in whom the electrical impulse stimulating the heart ventricles passes through the atrio-ventricular node, then symmetrically excites the branches of His bundle and finally the Purkinje fibers. In T1D patients, after proper onset of intraventricular stimulation, the isolines reflecting the both ventricles reach higher time values, which indicates problems in the propagation of the ventricular depolarization.
体表电位标测（BSPM）是一种用于检查患者体表心电图记录的多电极同步方法，可用于评估心脏传导系统的变化。本研究的目的是可视化并评估1型糖尿病青少年患者心室内系统的变化。
纳入标准：年龄>12岁，1型糖尿病病程>3年，糖化血红蛋白>8%。
自主神经病变、心脏结构缺陷、心力衰竭诊断。将BSPM数据处理成标测图，以说明心室激动时间（VAT，等时线）的差异。
纳入33名青少年（20名男性），平均年龄15.0±2.1岁，1型糖尿病病程6.8±4.1年。平均糖化血红蛋白为9.6±2.0%。在标准心电图记录中未发现异常。仅为1型糖尿病患者绘制的组均值图上等时线的分布最初类似于正常受试者（N = 30）组图上等时线的走向，在正常受试者中，刺激心室的电冲动通过房室结，然后对称地兴奋希氏束分支，最后兴奋浦肯野纤维。在1型糖尿病患者中，心室内刺激正常开始后，反映两个心室的等时线达到更高的时间值，这表明心室去极化的传播存在问题。
