不同手术时间对重症高血压性脑出血患者手术效果及生活质量的影响
Effect of different operation time on surgical effect and quality of life in patients with severe hypertensive intracerebral hemorrhage.
作者信息
Huang Yongyi, Zheng Hongjiang, Mo Minlong
机构信息
Department of Neurosurgery, Wuzhou Red Cross Hospital Wuzhou, Guangxi Autonomous Region, China.
Department of Intensive Care Unit, Wuzhou Red Cross Hospital Wuzhou, Guangxi Autonomous Region, China.
出版信息
Am J Transl Res. 2021 Aug 15;13(8):9538-9545. eCollection 2021.
OBJECTIVE
To investigate the effect of different operation time on the surgery effect and quality of life of patients with severe hypertensive cerebral hemorrhage.
METHODS
A total of 98 patients with severe hypertensive cerebral hemorrhage were selected in this prospective study. According to the random number table, 98 patients were divided into group A and group B. About 47 patients in group A received surgical treatment within 6 hours after onset of a cerebral hemorrhage and 51 patients in group B received surgical treatment within 6-24 hours after onset of a cerebral hemorrhage. The effect of the operation, quality of life (the World Health Organization Quality of Life Scale Brief Version, WHOQOL-BREF) score, neuro function (National Institute of Health stroke scale, NIHSS), the ability of daily living (Barthel index), athletic ability (Fugl-Meyer motor function score), complications and prognosis (GOS) were compared between the two groups.
RESULTS
The total effective rate of operation in group A (91.49%) was higher than that in group B (76.47%), and the incidence of complications (8.70%) was lower than that in group B (27.08%; all P<0.05). NIHSS score of group A was lower than that of group B, and the WHOQOL-BREF score was higher than that of group B three months after the operation (all P<0.05). Barthel Index and Fugl-Meyer motor function scores of group A were higher than those of group B three months after the operation (all P<0.05). The prognosis of group A was better than group B three months after the operation (P<0.05).
CONCLUSION
Operation performed within 6 hours after the onset of cerebral hemorrhage is useful in the treatment of severe hypertensive intracerebral hemorrhage. It can effectively improve patients' neurological function, the ability of daily living and motor function without increasing complications and, the quality of life, as well as the prognosis of patients.
目的
探讨不同手术时间对重症高血压性脑出血患者手术效果及生活质量的影响。
方法
本前瞻性研究共选取98例重症高血压性脑出血患者。根据随机数字表，将98例患者分为A组和B组。A组约47例患者在脑出血发病后6小时内接受手术治疗，B组51例患者在脑出血发病后6 - 24小时内接受手术治疗。比较两组患者的手术效果、生活质量（世界卫生组织生活质量量表简表，WHOQOL - BREF）评分、神经功能（美国国立卫生研究院卒中量表，NIHSS）、日常生活能力（Barthel指数）、运动能力（Fugl - Meyer运动功能评分）、并发症及预后（GOS）。
结果
A组手术总有效率（91.49%）高于B组（76.47%），并发症发生率（8.70%）低于B组（27.08%；均P<0.05）。术后3个月，A组NIHSS评分低于B组，WHOQOL - BREF评分高于B组（均P<0.05）。术后3个月，A组Barthel指数和Fugl - Meyer运动功能评分高于B组（均P<0.05）。术后3个月，A组预后优于B组（P<0.05）。
结论
脑出血发病后6小时内进行手术对重症高血压性脑出血的治疗有效。它可有效改善患者的神经功能、日常生活能力和运动功能，且不增加并发症，同时提高患者的生活质量及预后。
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