Yılmaz Ayşegül, Yazıcı Engin, Turk Can
Department of Medical Microbiology, School of Medicine, Lokman Hekim University, Ankara, Turkey.
Department of Immunology, School of Medicine, Gazi University, Ankara, Turkey.
Iran J Microbiol. 2021 Apr;13(2):243-247. doi: 10.18502/ijm.v13i2.5986.
Toxoplasmosis is a life-threatening zoonotic infection in immunosuppressive individuals. Determining the prevalence and seropositivity rates of toxoplasmosis in asymptomatic blood donors is crucial in terms of the risk status of the transmission of this infection to the blood recipients.
In this study, the presence and level of the specific IgG and IgM antibodies in blood donors was investigated by electrochemiluminescence immunoassay (ECLIA). The statistical significance levels between seropositivity and demographic characteristics of the donors such as age, educational status, raw meat consumption, drinking water supply were examined.
IgG seropositivity was found among the 225 (25.6%) of the donors present in the study group, while IgM seropositivity was detected in 20 donors (2.3%). The number of donors with only IgM (+) was 8 (0.9%). Both IgG and IgM seropositivities were found in 12 donors (1.4%).
Our study provides information about seropositivity based on the samples collected from the donors who were admitted to the blood center of a university hospital in Ankara, Turkey. This study demonstrates that seropositivity is high in the rural areas and the regions where the education level is low.
弓形虫病对免疫抑制个体而言是一种危及生命的人畜共患感染。就这种感染传播给输血受者的风险状况而言，确定无症状献血者中弓形虫病的患病率和血清阳性率至关重要。
在本研究中，采用电化学发光免疫分析法（ECLIA）检测献血者血液中特异性IgG和IgM抗体的存在情况及水平。研究了血清阳性与献血者的年龄、教育程度、生肉食用情况、饮用水供应等人口统计学特征之间的统计学显著性水平。
研究组中225名（25.6%）献血者检测出IgG血清阳性，20名（2.3%）献血者检测出IgM血清阳性。仅IgM（+）的献血者有8名（0.9%）。12名（1.4%）献血者同时检测出IgG和IgM血清阳性。
我们基于从土耳其安卡拉一所大学医院血液中心的献血者采集的样本，提供了关于血清阳性的信息。本研究表明农村地区和教育水平较低地区的血清阳性率较高。
