Sert Umit Yasemin, Ozgu-Erdinc A Seval, Gokay Sibel, Engin-Ustun Yaprak
a Dr. Zekai Tahir Burak Women's Health Care, Education and Research Hospital, University of Health Sciences , Ankara , Turkey.
Fetal Pediatr Pathol. 2019 Aug;38(4):307-316. doi: 10.1080/15513815.2019.1587122. Epub 2019 Mar 26.
To determine the seroprevalence of Toxoplasma in a tertiary referral center in Turkey and to discuss the benefits and drawbacks of routine antenatal screening. A serologic test for Toxoplasma is free of charge for all pregnant women as part of routine antenatal care at their first prenatal visit. The study was conducted between 2008 and 2017. : The frequency of Toxoplasma IgG and IgM seropositivity was 22.3% and 0.64%, respectively. Low avidity was detected in 142 patients and 60 PCR tests were performed with no positive result. A total of 33 mothers with low IgG avidity and negative PCR received prophylactic treatment, and no congenital toxoplasmosis was documented in this study. Universal screening for Toxoplasma in pregnancy is a subject of debate. As the prevalence in Turkey is higher compared to other countries, more studies are needed to identify the necessity of routine screening.
确定土耳其一家三级转诊中心弓形虫的血清流行率，并讨论常规产前筛查的利弊。作为常规产前护理的一部分，所有孕妇在首次产前检查时均可免费进行弓形虫血清学检测。该研究在2008年至2017年期间进行。结果显示，弓形虫IgG和IgM血清阳性率分别为22.3%和0.64%。在142例患者中检测到低亲和力，进行了60次PCR检测，均无阳性结果。共有33例IgG亲和力低且PCR阴性的母亲接受了预防性治疗，本研究中未记录到先天性弓形虫病病例。孕期普遍筛查弓形虫是一个有争议的话题。由于土耳其的患病率高于其他国家，需要更多研究来确定常规筛查的必要性。
