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德国一家大型中心对欧洲消化内镜学会(ESGE)关于新冠病毒病(COVID-19)内镜检查前风险分层建议的评估。

Evaluation of the ESGE recommendations for COVID-19 pre-endoscopy risk-stratification in a high-volume center in Germany.

作者信息

Zellmer Stephan, Ebigbo Alanna, Kahn Maria, Muzalyova Anna, Classen Johanna, Grünherz Vivian, Temizel Selin, Dhillon Christine, Messmann Helmut, Römmele Christoph

机构信息

Department of Gastroenterology and Infectious Diseases, University Hospital of Augsburg, Augsburg, Germany.

Department of Hygiene and Environmental Medicine, University Hospital of Augsburg, Augsburg, Germany.

出版信息

Endosc Int Open. 2021 Sep 16;9(10):E1556-E1560. doi: 10.1055/a-1526-1169. eCollection 2021 Oct.

DOI:10.1055/a-1526-1169
PMID:34540550
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8445688/
Abstract

The European Society of Gastrointestinal Endoscopy (ESGE) has defined COVID-19 infection prevention and control strategies within the endoscopy unit. These include pre-endoscopic questionnaire-based risk-stratification as well as pre-procedure viral testing. Real-life data on the effectiveness of these measures are presented here. Data from the outpatient endoscopic unit of the University Hospital Augsburg between July 1, 2020 and December 31, 2020 including the second pandemic wave were reviewed retrospectively. All patients were assessed with a pre-endoscopic risk-stratification questionnaire as well as viral testing using an antigen point-of-care test (Ag-POCT) in conjunction with a standard polymerase chain reaction (PCR) test. Highly elective procedures were postponed. The theoretically expected number of SARS-CoV-2-positive patients was simulated and compared with the actual number. In addition, endoscopy staff was evaluated with a rapid antibody test to determine the number of infections among the personnel. In total, 1029 procedures, 591 questionnaires, 591 Ag-POCTs, and 529 standard PCR tests were performed in 591 patients. 247 procedures in 142 patients were postponed. One Ag-POCT was positive but with a negative PCR test, while one PCR test was positive but with a negative Ag-POCT. This was lower than the theoretically expected number of COVID-19-positive patients (n = 15). One of 43 employees (2.3 %) in the outpatient endoscopy unit was seropositive. Pre-endoscopic risk management including questionnaire-based risk stratification and viral testing seems to be an effective tool in combination with personal protective equipment for SARS-CoV-2 infection prevention and control within the endoscopy unit even in a high-prevalence setting.

摘要

欧洲胃肠内镜学会(ESGE)已制定了内镜检查科室的新冠病毒感染预防与控制策略。这些策略包括基于内镜检查前问卷的风险分层以及检查前的病毒检测。本文展示了这些措施有效性的实际数据。对奥格斯堡大学医院门诊内镜科室2020年7月1日至2020年12月31日期间的数据进行了回顾性分析,这一时期包括第二波疫情。所有患者均通过内镜检查前风险分层问卷进行评估,并使用即时检测抗原检测(Ag-POCT)结合标准聚合酶链反应(PCR)检测进行病毒检测。高选择性手术被推迟。模拟了理论上预计的新冠病毒阳性患者数量,并与实际数量进行比较。此外,通过快速抗体检测对内镜检查工作人员进行评估,以确定工作人员中的感染人数。总共对591例患者进行了1029例手术、591份问卷、591次Ag-POCT检测和529次标准PCR检测。142例患者的247例手术被推迟。1次Ag-POCT检测呈阳性但PCR检测呈阴性,1次PCR检测呈阳性但Ag-POCT检测呈阴性。这低于理论上预计的新冠病毒阳性患者数量(n = 15)。门诊内镜科室43名员工中有1名(2.3%)血清学检测呈阳性。内镜检查前风险管理,包括基于问卷的风险分层和病毒检测,似乎是在内镜科室预防和控制新冠病毒感染的有效工具,即使在高流行环境下,结合个人防护装备使用也是如此。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9a/8445688/653171b9494f/10-1055-a-1526-1169-i2335ei2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9a/8445688/9995edb8ae57/10-1055-a-1526-1169-i2335ei1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9a/8445688/653171b9494f/10-1055-a-1526-1169-i2335ei2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9a/8445688/9995edb8ae57/10-1055-a-1526-1169-i2335ei1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9a/8445688/653171b9494f/10-1055-a-1526-1169-i2335ei2.jpg

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