两例由隐球菌属隐匿种引起侵袭性真菌性鼻鼻窦炎的猫对联合抗真菌治疗产生完全临床反应

Kay Alexandra, Boland Lara, Kidd Sarah E, Beatty Julia A, Talbot Jessica J, Barrs Vanessa R

Brunswick Central Vet Clinic, 210 Lygon Street, Brunswick East, VIC, 3055, Australia.

University of Sydney, Faculty of Science, Sydney School of Veterinary Science, Sydney, NSW, 2006, Australia.

Med Mycol Case Rep. 2021 Sep 2;34:13-17. doi: 10.1016/j.mmcr.2021.08.005. eCollection 2021 Dec.

Cryptic species in section are increasingly reported to cause invasive aspergillosis in humans and animals. These infections are often refractory to treatment because of intrinsic antifungal resistance. We report two cases of invasive fungal rhinosinusitis in domestic cats caused by and . Clinical signs resolved after combined therapy including posaconazole, caspofungin and terbinafine. Both cases remained asymptomatic more than 2 years from initial presentation.

该属中的隐秘菌种越来越多地被报道可导致人类和动物的侵袭性曲霉病。由于固有的抗真菌耐药性，这些感染往往难以治疗。我们报告了两例由[未提及具体菌种]引起的家猫侵袭性真菌性鼻-鼻窦炎病例。包括泊沙康唑、卡泊芬净和特比萘芬在内的联合治疗后临床症状得到缓解。自初次就诊以来，两例病例在超过2年的时间里均无症状。