Wang Zhe, Daniels Joshua B, Lappin Michael, Aboellail Tawfik, Shropshire Sarah
Department of Clinical Sciences, Colorado State University, Fort Collins, CO, USA.
Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA.
JFMS Open Rep. 2023 Jul 6;9(2):20551169231181863. doi: 10.1177/20551169231181863. eCollection 2023 Jul-Dec.
This report describes an indoor-only cat with a rare form of sino-orbital aspergillosis (SOA) with cervical lymphadenopathy causing local obstruction. Extensive work-up on initial presentation failed to identify the underlying etiology and the diagnosis was not determined until the disease progressed during a prolonged course of glucocorticoid therapy.
SOA caused by complex is increasingly recognized as a significant cause of mortality in cats in recent years, with most cases reported in Australia, Europe and Asia. Feline SOA carries a poor prognosis owing to its invasive nature and resistance to antifungal therapy. This case demonstrates the importance of clinical awareness of SOA as a differential for cats with chronic nasal signs and exophthalmos in the USA. Moreover, it demonstrates a rare form of presentation and potential difficulty in achieving a correct diagnosis.
本报告描述了一只仅在室内饲养的猫,患有罕见形式的鼻窦眶曲霉病(SOA),伴有颈部淋巴结病导致局部阻塞。初次就诊时进行的广泛检查未能确定潜在病因,直到在长期糖皮质激素治疗过程中病情进展才确诊。
近年来,由曲霉菌引起的SOA越来越被认为是猫死亡的重要原因,大多数病例报告于澳大利亚、欧洲和亚洲。猫SOA因其侵袭性和对抗真菌治疗的耐药性而预后不良。该病例表明在美国临床认识到SOA作为慢性鼻症状和眼球突出猫的鉴别诊断的重要性。此外,它还展示了一种罕见的表现形式以及在做出正确诊断方面可能存在的困难。