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一种营养补充剂配方对提高健康受试者的循环维生素和矿物质水平有效:一项随机试验。

A Nutraceutical Formula Is Effective in Raising the Circulating Vitamin and Mineral Levels in Healthy Subjects: A Randomized Trial.

作者信息

Nenseth Hatice Zeynep, Sahu Aparna, Saatcioglu Fahri, Osguthorpe Steven

机构信息

Department of Biosciences, University of Oslo, Oslo, Norway.

Turiyan Psyneuronics Pvt. Ltd, Bangalore, India.

出版信息

Front Nutr. 2021 Sep 1;8:703394. doi: 10.3389/fnut.2021.703394. eCollection 2021.

DOI:10.3389/fnut.2021.703394
PMID:34540877
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8440802/
Abstract

Low levels of nutrient intake are common in industrialized countries. This has negative implications on health and is associated with chronic diseases. Supplementation of vitamins, minerals, and key nutrients to optimal levels may, therefore, be beneficial for individual health and for the health economy. Although the use of supplements has become very common, due to a lack of monitoring, there is very limited data on the efficacy of supplementation with different formulas. In this study, we present the results of a randomized controlled study on the efficacy of a novel formulated nutraceutical, N247, in 250 healthy volunteers aged 26-75 years and a placebo control group ( = 35). The broad-spectrum formulation of N247 includes essential vitamins, minerals, and trace elements that are adequately balanced in regard to synergies and related metabolic functions. Moreover, tolerance, safety, and nutrient availability is an important aspect of daily, long-term use of N247. After 3 months of regular N247 use, levels of vitamins and minerals in serum were significantly increased in the N247 group compared with the control group and a placebo group, with excellent compliance rates. Coupled with additional natural ingredients that aim to increase the potency of the nutrients, N247 may represent a novel and beneficial supplement for individuals with nutritional deficiencies. https://clinicaltrials.gov/, identifier: NCT04054505.

摘要

在工业化国家,低水平的营养摄入很常见。这对健康有负面影响,并与慢性病相关。因此,将维生素、矿物质和关键营养素补充到最佳水平可能对个人健康和健康经济有益。尽管补充剂的使用已经非常普遍,但由于缺乏监测,关于不同配方补充剂功效的数据非常有限。在本研究中,我们展示了一项针对250名年龄在26至75岁的健康志愿者和一个安慰剂对照组(n = 35)的新型营养保健品N247功效的随机对照研究结果。N247的广谱配方包括必需维生素、矿物质和微量元素,它们在协同作用和相关代谢功能方面得到了充分平衡。此外,耐受性、安全性和营养可利用性是N247日常长期使用的一个重要方面。在定期使用N247三个月后,与对照组和安慰剂组相比,N247组血清中的维生素和矿物质水平显著升高,依从率极佳。再加上旨在增强营养成分效力的其他天然成分,N247可能是一种对营养缺乏个体新颖且有益的补充剂。https://clinicaltrials.gov/,标识符:NCT04054505。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f46/8440802/0b21a6aed4ca/fnut-08-703394-g0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f46/8440802/85d0be8d5bf4/fnut-08-703394-g0001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f46/8440802/0b21a6aed4ca/fnut-08-703394-g0007.jpg

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本文引用的文献

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2
Mechanistic insights into the treatment of iron-deficiency anemia and arthritis in humans with dietary molybdenum.膳食钼治疗人类缺铁性贫血和关节炎的作用机制研究。
Eur J Clin Nutr. 2021 Aug;75(8):1170-1175. doi: 10.1038/s41430-020-00845-7. Epub 2021 Jan 29.
3
COVID-19 pandemic and mitigation strategies: implications for maternal and child health and nutrition.COVID-19 大流行及缓解策略:对母婴健康和营养的影响。
Am J Clin Nutr. 2020 Aug 1;112(2):251-256. doi: 10.1093/ajcn/nqaa171.
4
Safety and clinical effectiveness of Withania Somnifera (Linn.) Dunal root in human ailments.睡茄(印度人参)根在人类疾病中的安全性和临床功效。
J Ethnopharmacol. 2020 Jun 12;255:112768. doi: 10.1016/j.jep.2020.112768. Epub 2020 Mar 19.
5
B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin.神经系统中的 B 族维生素:硫胺素、吡哆醇和钴胺素的生化作用模式和协同作用的当前知识。
CNS Neurosci Ther. 2020 Jan;26(1):5-13. doi: 10.1111/cns.13207. Epub 2019 Sep 6.
6
Resveratrol derivatives increase cytosolic calcium by inhibiting plasma membrane ATPase and inducing calcium release from the endoplasmic reticulum in prostate cancer cells.白藜芦醇衍生物通过抑制质膜ATP酶并诱导前列腺癌细胞内质网释放钙来增加胞质钙。
Biochem Biophys Rep. 2019 Jul 20;19:100667. doi: 10.1016/j.bbrep.2019.100667. eCollection 2019 Sep.
7
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Lancet Public Health. 2019 Mar;4(3):e159-e167. doi: 10.1016/S2468-2667(19)30019-2.
8
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9
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Vitamin B₆ and Its Role in Cell Metabolism and Physiology.维生素B₆及其在细胞代谢和生理学中的作用。
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