中重度 COVID-19 患者的微循环血液动力学状态。
The State of Microcirculatory Hemodynamics in Patients with Moderate and Severe COVID-19.
机构信息
Chita State Medical Academy, Ministry of Health of the Russian Academy, Chita, Russia.
出版信息
Bull Exp Biol Med. 2021 Aug;171(4):453-457. doi: 10.1007/s10517-021-05248-7. Epub 2021 Sep 20.
Microcirculatory hemodynamic indexes (HI) were assessed in patients with moderate and severe COVID-19. In both groups, a significant increase in the absolute spectral indexes (HI1, HI2, and HI3) and the ratio of low-frequency to high-frequency component (HI1/HI3) was revealed. In the group of severe infection, only the "slow" index (low-frequency HI1) of microcirculatory hemodynamics was significantly lower. The oscillatory indices MAYER1-3 and RESP1-3 were reduced in patients of both groups. The aggravation of the disease course was accompanied by depression of the low-frequency index HI1. Regulatory shifts compensate for disturbances in microcirculatory processes in moderate COVID-19, but severe course was associated with their decompensation.
评估了中重度 COVID-19 患者的微循环血液动力学指标 (HI)。在两组中，绝对频谱指标 (HI1、HI2 和 HI3) 和低频与高频成分比 (HI1/HI3) 均显著增加。在严重感染组中，仅微循环血液动力学的“缓慢”指数 (低频 HI1) 显著降低。两组患者的 MAYER1-3 和 RESP1-3 震荡指数均降低。疾病病程加重伴随着低频指数 HI1 的抑制。在中度 COVID-19 中，调节转移可补偿微循环过程的紊乱，但严重病程与它们的失代偿有关。
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