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从100单位/毫升转换至200单位/毫升赖脯胰岛素笔的满意度、偏好及注射习惯:德国一项患者调查

Satisfaction, Preference and Injection Habits of Switching to 200 Units/ml Insulin Lispro Pen from 100 Units/ml: A Patient Survey in Germany.

作者信息

Chen Jieling, Williams Paul, Perez-Nieves Magaly, Piras De Oliveira Carolina, Spaepen Erik, Osumili Beatrice, Poon Jiat-Ling, Schloot Nanette C, Thun Barbara, Blüher Matthias

机构信息

Lilly Corporate Center, Indianapolis, IN, 46285, USA.

IQVIA, Real-World Solutions, 17 bis place des Reflets, Tour D2, TSA 64567, 92099, La Defense Cedex, France.

出版信息

Diabetes Ther. 2021 Nov;12(11):2939-2953. doi: 10.1007/s13300-021-01150-7. Epub 2021 Sep 20.

Abstract

INTRODUCTION

The study was designed to assess patient satisfaction, preferences and injection habits for patients using insulin lispro 200 units/ml pen (IL200) compared to their previously used disposable 100 units/ml mealtime insulin pen ("MTI-100 pen") in Germany.

METHODS

A site-based, cross-sectional study involving a self-reported survey and medical record extraction in patients with diabetes currently using IL200 for between 3 and 12 months and had previously used any disposable MTI-100 pen.

RESULTS

Of 114 patients included, 83.3% were satisfied with IL200 and 3.5% were dissatisfied; 70.2% preferred IL200 over their previous MTI-100 pen and 4.4% preferred their previous MTI-100 pen. The main reasons for IL200 preference were the amount of insulin the pen carries, longer use before discarding, number of non-empty pens discarded, injection volume and frequency replacing pens. Patients discarded (median) 4 IL200 pens per month with 5.3% discarding more than 10 units in their last pen. When insufficient insulin remained to complete a dose, 74.6% injected the remainder and completed with a new pen, 19.3% discarded the pen with remaining insulin, 7.0% saved it for future use and 1.8% left the dose incomplete.

CONCLUSIONS

Satisfaction and preference for IL200 was high in this sample of patients using IL200 for 3-12 months. Reasons were consistent with IL200 features, explaining the better patient experience and potential resource saving transitioning from a disposable MTI-100 pen.

摘要

引言

本研究旨在评估在德国使用200单位/毫升赖脯胰岛素笔(IL200)的患者与他们之前使用的一次性100单位/毫升餐时胰岛素笔(“MTI - 100笔”)相比的患者满意度、偏好和注射习惯。

方法

一项基于站点的横断面研究,涉及对目前使用IL200达3至12个月且之前使用过任何一次性MTI - 100笔的糖尿病患者进行自我报告调查和病历提取。

结果

在纳入的114名患者中,83.3%对IL200满意,3.5%不满意;70.2%的患者更喜欢IL200而非他们之前的MTI - 100笔,4.4%更喜欢他们之前的MTI - 100笔。偏爱IL200的主要原因是笔携带的胰岛素量、丢弃前的使用时间更长、丢弃的非空笔数量、注射量以及更换笔的频率。患者每月(中位数)丢弃4支IL200笔,5.3%的患者在最后一支笔中丢弃超过10单位。当剩余胰岛素不足以完成一剂注射时,74.6%的患者注射了剩余部分并用新笔完成注射,19.3%的患者丢弃了含有剩余胰岛素的笔,7.0%的患者将其留作未来使用,1.8%的患者未完成剂量注射。

结论

在使用IL200达3至12个月的该患者样本中,对IL200的满意度和偏好较高。原因与IL200的特性一致,这解释了从一次性MTI - 100笔过渡时更好的患者体验和潜在的资源节约。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c443/8519973/9c64af19a7da/13300_2021_1150_Fig1_HTML.jpg

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