Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.
Anal Chem. 2021 Oct 5;93(39):13106-13111. doi: 10.1021/acs.analchem.1c01247. Epub 2021 Sep 21.
We report here on a new generation of optical ion-selective sensors benefiting from cubosomes or hexosomes-nanostructural lipid liquid phase. Cubosome as well as hexosome optodes offer biocompatibility, self-assembly preparation, high stability in solution, and unique, tunable analytical performance. The temperature trigger reversibly changes the lipid nanoparticle internal structure-changing analyte access to the bulk of the probe and ultimately affecting the response pattern. Thus, cubosome or hexosome optodes are highly promising alternatives to conventional polymeric based optical nanoprobes.
我们在此报告受益于立方相或六方相纳米结构脂质液相的新一代光学离子选择性传感器。立方相和六方相光导纤维提供生物相容性、自组装制备、高溶液稳定性以及独特、可调的分析性能。温度触发可使脂质纳米颗粒的内部结构发生可逆变化，从而改变分析物进入探针主体的方式，并最终影响响应模式。因此，立方相或六方相光导纤维是对传统聚合物基光学纳米探针的极具前景的替代方案。
