Montoneri C, Zarbo G, Garofalo A, Giardinella S
First Clinic of Obstetrics and Gynecology, University of Catania, Italy.
Clin Exp Obstet Gynecol. 1987;14(3-4):178-81.
Forty eight women with atrophic endometrium were treated with estriol, 1 mg twice daily, by mouth for a minimum of 10 days and a maximum of 25 days. Vaginal hysterectomy was then performed and specimens were examined histologically. Results showed that estriol produces endometrial hyperplasia in 70.8% of the examined women; only 29.2% of the patients retained atrophic endometrium after treatment.
