Lee W R
Pathology Department, Western Infirmary, Glasgow.
Eye (Lond). 1987;1 ( Pt 6):668-75. doi: 10.1038/eye.1987.109.
This report describes the macroscopic and microscopic features of 'pseudomelanomas' encountered in 48 globes containing malignant melanomas, which were initially treated either by local resection (45), by Ru106 plaque (2) therapy or by photocoagulation (1) therapy. Pigmented masses which stimulated melanomas were formed by (i) organising haemorrhage, (ii) melanomacrophagic reactions to melanin released from necrotic tumours, (iii) reactionary proliferations in the retinal pigment epithelium. Fibroblastic reactions in response to photocoagulation or organising haemorrhage also produced pseudotumours.
本报告描述了在48个含有恶性黑色素瘤的眼球中遇到的“假黑色素瘤”的大体和微观特征，这些眼球最初接受了局部切除（45例）、钌106敷贴（2例）或光凝（1例）治疗。刺激黑色素瘤形成的色素性肿块是由以下因素形成的：（i）机化性出血，（ii）对坏死肿瘤释放的黑色素的黑色素巨噬细胞反应，（iii）视网膜色素上皮的反应性增生。对光凝或机化性出血的成纤维细胞反应也产生了假肿瘤。
