Vit V V
Arkh Patol. 1985;47(7):23-9.
Investigation of 121 uveal melanomas revealed three stages of postcoagulation changes: destruction connected with the immediate coagulating effect of the radiation (from 1 to 14 days after coagulation); inflammation and destruction changes displaying the antitumour immune response and accompanied by the increased functional activity of the survived melanoma cells (from 2 weeks till 2-4 months); fibrotization of the most damaged parts of melanoma tissue and structural and functional reorganization of some melanoma cells with the signs of their greater atypia. Melanomas of different cell type composition react to coagulation differently, this is manifested by the intensity, duration and reversibility of functional changes of tumour cells and also by the probability of their greater atypia.
对121例葡萄膜黑色素瘤的研究揭示了凝固后变化的三个阶段：与辐射的即时凝固效应相关的破坏（凝固后1至14天）；显示抗肿瘤免疫反应并伴有存活黑色素瘤细胞功能活性增加的炎症和破坏变化（从2周直至2 - 4个月）；黑色素瘤组织最受损部分的纤维化以及一些黑色素瘤细胞的结构和功能重组，伴有细胞异型性增加的迹象。不同细胞类型组成的黑色素瘤对凝固的反应不同，这表现为肿瘤细胞功能变化的强度、持续时间和可逆性，以及细胞异型性增加的可能性。
