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[Clinical and biological characteristics and prognosis of patients with biclonal multiple myeloma].[双克隆多发性骨髓瘤患者的临床及生物学特征与预后]
Zhonghua Xue Ye Xue Za Zhi. 2021 Aug 14;42(8):677-679. doi: 10.3760/cma.j.issn.0253-2727.2021.08.011.
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The clinical aspects of biclonal gammopathies. Review of 57 cases.双克隆丙种球蛋白病的临床情况。57例病例回顾。
Am J Med. 1981 Dec;71(6):999-1008. doi: 10.1016/0002-9343(81)90326-0.
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Clinical aspects of biclonal myelomas.双克隆骨髓瘤的临床特征
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Similar survival outcomes in patients with biclonal versus monoclonal myeloma: a multi-institutional matched case-control study.
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Immunoglobulin G kappa biclonal gammopathy associated with multiple myeloma, plasmacytoma and cast nephropathy.与多发性骨髓瘤、浆细胞瘤和管型肾病相关的免疫球蛋白G κ 双克隆丙种球蛋白病
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Response comparison of multiple myeloma and monoclonal gammopathy of undetermined significance to the same anti-myeloma therapy: a retrospective cohort study.多发性骨髓瘤与意义未明的单克隆丙种球蛋白病对相同抗骨髓瘤治疗的反应比较：一项回顾性队列研究
Lancet Haematol. 2017 Dec;4(12):e584-e594. doi: 10.1016/S2352-3026(17)30209-0. Epub 2017 Nov 13.
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Immunoglobulin heavy and light chain isotypes in multiple myeloma patients.多发性骨髓瘤患者的免疫球蛋白重链和轻链同种型
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Clinical characteristics and outcomes in biclonal gammopathies.双克隆丙种球蛋白病的临床特征与转归
Am J Hematol. 2016 May;91(5):473-5. doi: 10.1002/ajh.24319. Epub 2016 Apr 6.
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A case of IgD myeloma representing a missed biclonal paraproteinemia or isotype switch in a patient previously diagnosed with IgA-lambda myeloma.一例 IgD 型骨髓瘤代表了先前诊断为 IgA-λ 型骨髓瘤患者中漏检的双克隆副蛋白血症或同种型转换。
Clin Chim Acta. 2013 Oct 21;425:233-5. doi: 10.1016/j.cca.2013.08.004. Epub 2013 Aug 13.
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Biclonal and hypodiploid multiple myeloma.
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First-line anti-BCMA CAR-T cell therapy in a fragile patient with biclonal gammopathy and giant plasma cell tumor multiple myeloma with multiple comorbidities: a case report.一线抗BCMA嵌合抗原受体T细胞疗法治疗一名患有双克隆丙种球蛋白病和巨大浆细胞肿瘤的多发性骨髓瘤且合并多种疾病的脆弱患者：一例报告
Front Immunol. 2025 Apr 16;16:1564774. doi: 10.3389/fimmu.2025.1564774. eCollection 2025.

本文引用的文献

1
A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis.通过基因组分析鉴定的一组新诊断骨髓瘤的高危、双重打击群体。
Leukemia. 2019 Jan;33(1):159-170. doi: 10.1038/s41375-018-0196-8. Epub 2018 Jul 2.
2
Similar survival outcomes in patients with biclonal versus monoclonal myeloma: a multi-institutional matched case-control study.
Ann Hematol. 2017 Oct;96(10):1693-1698. doi: 10.1007/s00277-017-3084-9. Epub 2017 Aug 1.
3
A Rare Case of Multiple Myeloma with Biclonal Gammopathy.一例罕见的伴有双克隆丙种球蛋白病的多发性骨髓瘤
J Clin Diagn Res. 2016 Dec;10(12):BD03-BD04. doi: 10.7860/JCDR/2016/22466.8984. Epub 2016 Dec 1.
4
Occurrence of Double Monoclonal Bands on Protein Electrophoresis: An Unusual Finding.蛋白质电泳中出现双单克隆条带：一项不寻常的发现。
Indian J Hematol Blood Transfus. 2016 Jun;32(Suppl 1):184-8. doi: 10.1007/s12288-015-0622-2. Epub 2015 Nov 28.
5
Treatment of multiple myeloma with high-risk cytogenetics: a consensus of the International Myeloma Working Group.高危细胞遗传学特征的多发性骨髓瘤的治疗：国际骨髓瘤工作组共识
Blood. 2016 Jun 16;127(24):2955-62. doi: 10.1182/blood-2016-01-631200. Epub 2016 Mar 21.
6
Clinical characteristics and outcomes in biclonal gammopathies.双克隆丙种球蛋白病的临床特征与转归
Am J Hematol. 2016 May;91(5):473-5. doi: 10.1002/ajh.24319. Epub 2016 Apr 6.
7
Multiple Myeloma: Diagnosis and Treatment.多发性骨髓瘤：诊断与治疗
Mayo Clin Proc. 2016 Jan;91(1):101-19. doi: 10.1016/j.mayocp.2015.11.007.
8
Secondary monoclonal gammopathy of undetermined significance is frequently associated with high response rate and superior survival in patients with plasma cell dyscrasias.意义未明的单克隆免疫球蛋白血症继发者在浆细胞疾病患者中具有较高的缓解率和更好的生存。
Biol Blood Marrow Transplant. 2014 Mar;20(3):319-25. doi: 10.1016/j.bbmt.2013.11.022. Epub 2013 Dec 1.
9
Incidence, clinical course, and prognosis of secondary monoclonal gammopathy of undetermined significance in patients with multiple myeloma.多发性骨髓瘤患者伴意义未明的单克隆丙种球蛋白血症的发生率、临床经过和预后。
Blood. 2011 Sep 15;118(11):2985-7. doi: 10.1182/blood-2011-04-349175. Epub 2011 Jul 15.
10
Polymorphisms of nuclear factor-κB family genes are associated with development of multiple myeloma and treatment outcome in patients receiving bortezomib-based regimens.核因子-κB 家族基因的多态性与接受硼替佐米为基础方案的患者多发性骨髓瘤的发展和治疗结果相关。
Haematologica. 2011 May;96(5):729-37. doi: 10.3324/haematol.2010.030577. Epub 2011 Jan 12.

[Clinical and biological characteristics and prognosis of patients with biclonal multiple myeloma].

作者信息

Cheng W, Li Y L, Huang Z F, Li Z B, Dong X Y, Shang B J, Zhang L, Shi J, Zhu Z M

机构信息

Department of Hematology, Zhengzhou University People's Hospital, Institute of Hematology, Henan Province People's Hospital, Henan Key Laboratory of Stem Cell Regulation and Differentiation, Zhengzhou 450003, China.

出版信息

Zhonghua Xue Ye Xue Za Zhi. 2021 Aug 14;42(8):677-679. doi: 10.3760/cma.j.issn.0253-2727.2021.08.011.

DOI:10.3760/cma.j.issn.0253-2727.2021.08.011
PMID:34547875
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8501275/
Abstract
摘要