Department of Neonatology, Birmingham Women's Hospital NHS Trust, Birmingham, United Kingdom.
Department of Neonatology, Birmingham Women's Hospital NHS Trust, Birmingham, United Kingdom; Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Early Hum Dev. 2021 Nov;162:105457. doi: 10.1016/j.earlhumdev.2021.105457. Epub 2021 Sep 1.
The possibility of pulse oximetry screening (POS) for congenital heart defects was first described over 20 years ago. Since then, an accumulation of research evidence and clinical practice experience has established POS as an important test to detect critical congenital heart defects (CCHDs). POS meets the criteria for universal screening and professional bodies around the globe have recommended universal POS. Many countries have already adopted POS while several others are working towards its implementation. In low and low-middle-income countries (LLMIC), POS has the additional potential for reducing morbidity and mortality from neonatal sepsis. This review summarises the evidence for POS and looks at current global uptake and different approaches to the implementation of POS.
脉搏血氧饱和度筛查(POS)用于先天性心脏病的可能性早在 20 多年前就已被描述。从那时起,大量的研究证据和临床实践经验已经确立了 POS 作为检测严重先天性心脏病(CCHD)的重要检测手段。POS 符合普遍筛查的标准,全球专业机构都推荐进行普遍的 POS 筛查。许多国家已经采用了 POS,而其他一些国家也正在努力实施。在低收入和中低收入国家(LLMIC),POS 还有可能降低新生儿败血症的发病率和死亡率。本综述总结了 POS 的证据,并探讨了当前全球的采用情况和实施 POS 的不同方法。