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问卷调查与乳酸刺痛试验在敏感性皮肤评估中发挥不同作用:一项横断面研究

Questionnaire and Lactic Acid Sting Test Play Different Role on the Assessment of Sensitive Skin: A Cross-sectional Study.

作者信息

Pan Yao, Ma Xue, Song Yanqing, Zhao Jinfeng, Yan Shiyu

机构信息

Department of Cosmetics, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, 100048, People's Republic of China.

Beijing Key Laboratory of Plant Research and Development, Beijing, 100048, People's Republic of China.

出版信息

Clin Cosmet Investig Dermatol. 2021 Sep 14;14:1215-1225. doi: 10.2147/CCID.S325166. eCollection 2021.

Abstract

BACKGROUND

Questionnaires and lactic acid sting test (LAST) are two widely used methods to identify sensitive skin. However, the self-perceived sensitive skin by questionnaires was not consistent with the determination of LAST.

OBJECTIVE

The aim of the study was to measure the biophysical properties noninvasively of sensitive skin evaluated by questionnaire and LAST and to investigate their correlations with the scores of questionnaire and LAST.

METHODS

A total of 209 healthy Chinese females completed the study. Self-assessment questionnaire and LAST were both performed to identify sensitive skin. Epidermal biophysical properties, including skin hydration, transepidermal water loss (TEWL), sebum content, erythema index (EI), a* value, L* value, skin elasticity, and skin pH, were measured with noninvasive instruments.

RESULTS

The frequency of sensitive skin was 50.2% and 66.0% by questionnaire and LAST, respectively. Subjects with self-assessed sensitive skin had a slightly higher LAST positive rate. Skin hydration, sebum content, a* and EI values were significantly higher in the self-assessed sensitive skin group, while TEWL, a* and EI values increased but L* value decreased with significance in the LAST positive group. The LAST stingers among sensitive skin subjects had higher EI but not in the healthy skin subjects. In addition, questionnaire scores positively correlated with skin hydration, sebum content, a* and EI values, while a positive relationship of LAST scores with TEWL, a* and EI values was observed. The scores of questionnaire and LAST both negatively related to L* value.

CONCLUSION

Self-assessed questionnaire is associated with sensitive skin featured by oily and red face without impaired barrier function, whereas LAST is suitable to identify fragile skin barrier and enhanced blood flow on the face. Combination of both methods to diagnose sensitive skin might be more reliable.

摘要

背景

问卷调查和乳酸刺痛试验(LAST)是两种广泛用于识别敏感性皮肤的方法。然而,通过问卷调查自我感知的敏感性皮肤与LAST的测定结果并不一致。

目的

本研究旨在通过问卷调查和LAST评估敏感性皮肤的生物物理特性,并探讨它们与问卷调查和LAST评分的相关性。

方法

共有209名健康中国女性完成了本研究。通过自我评估问卷和LAST来识别敏感性皮肤。使用无创仪器测量表皮生物物理特性,包括皮肤水分含量、经表皮水分流失(TEWL)、皮脂含量、红斑指数(EI)、a值、L值、皮肤弹性和皮肤pH值。

结果

通过问卷调查和LAST评估的敏感性皮肤发生率分别为50.2%和66.0%。自我评估为敏感性皮肤的受试者LAST阳性率略高。自我评估为敏感性皮肤的人群中,皮肤水分含量、皮脂含量、a值和EI值显著更高,而LAST阳性组中TEWL、a值和EI值升高,但L值显著降低。敏感性皮肤受试者中的LAST刺痛者EI更高,但健康皮肤受试者中并非如此。此外,问卷评分与皮肤水分含量、皮脂含量、a值和EI值呈正相关,而LAST评分与TEWL、a值和EI值呈正相关。问卷和LAST评分均与L值呈负相关。

结论

自我评估问卷与以面部油腻、发红且屏障功能未受损为特征的敏感性皮肤相关,而LAST适用于识别面部脆弱的皮肤屏障和增强的血流。两种方法联合诊断敏感性皮肤可能更可靠。

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