Haberal Miktat Arif, Akar Erkan, Dikis Ozlem Sengoren, Ay Mehmet Oguzhan, Demirci Hakan
Department of Thoracic Surgery, Bursa Yuksek Ihtisas Training and Research Hospital, Health Sciences University, Bursa, Turkey.
Department of Pulmonary Medicine, Bursa Yuksek Ihtisas Training and Research Hospital, Health Sciences University, Bursa, Turkey.
Clinics (Sao Paulo). 2021 Sep 20;76:e2959. doi: 10.6061/clinics/2021/e2959. eCollection 2021.
To evaluate the presentation characteristics and disease course of seven patients with COVID-19 who spontaneously developed pneumomediastinum without a history of mechanical ventilation.
A total of seven non-intubated patients with COVID-19, of age ranging from 18-67 years, who developed spontaneous pneumomediastinum between 01 April and 01 October 2020 were included in the study. Patients' demographic data, clinical variables, and laboratory values were examined. Spontaneous pneumomediastinum was evaluated using posteroanterior chest radiography and thorax computed tomography.
During the research period, 38,492 patients reported to the emergency department of our hospital with COVID-19 symptoms. Of these, spontaneous pneumomediastinum was detected in seven patients who had no previous history of intubation. Chronic obstructive pulmonary disease (2/7) and asthma bronchiale (2/7) were determined as the most common causes of comorbidity.
In our study, the frequency of spontaneous pneumomediastinum developing without pneumothorax was found to be high in non-intubated patients. Whether this is related to the nature of the disease or it is a result of the increase in cases diagnosed incidentally owing to the increasing use of low-dose computed tomography should be explored in further studies.
评估7例新型冠状病毒肺炎（COVID-19）患者的临床表现特征及病程，这些患者在无机械通气史的情况下自发发生纵隔气肿。
本研究纳入了2020年4月1日至10月1日期间共7例年龄在18至67岁之间、未进行气管插管的COVID-19患者，这些患者自发发生了纵隔气肿。对患者的人口统计学数据、临床变量和实验室值进行了检查。使用胸部正位X线片和胸部计算机断层扫描评估自发纵隔气肿。
在研究期间，我院急诊科共收治了38492例有COVID-19症状的患者。其中，7例既往无插管史的患者被检测出自发纵隔气肿。慢性阻塞性肺疾病（2/7）和支气管哮喘（2/7）被确定为最常见的合并症原因。
在我们的研究中，未插管患者中无气胸的自发纵隔气肿发生率较高。这是否与疾病的性质有关，或者是由于低剂量计算机断层扫描使用增加导致偶然诊断病例增加的结果，应在进一步研究中进行探索。
