Levitsky S, Feinberg H
Surg Annu. 1978;10:305-20.
It appears obvious that in evaluating gross mortality and morbidity, clinical statistics are insufficient to demonstrate which form of a myocardial protective measure is safest. Previous studies indicate that significant ischemic injury may not be detectable by routine measurements of contractility. Only microscopic examination of the heart at a later period will allow detection of the patchy ischemic injury. In patients, loss of cardiac reserve as measured by postoperative catheterization, particularly compliance studies, and stress testing may be the final clinical arbiter of this controversy.
显然,在评估总死亡率和发病率时,临床统计数据不足以证明哪种心肌保护措施形式最安全。先前的研究表明,通过常规收缩性测量可能无法检测到明显的缺血性损伤。只有在后期对心脏进行显微镜检查才能发现散在的缺血性损伤。对于患者,术后通过导管插入术测量的心脏储备功能丧失,尤其是顺应性研究和压力测试,可能是这场争论的最终临床裁决者。