Shi S X
Department of Psychiatry, Huashan Hospital of Fudan University,Shanghai 200040,China,Email:
Zhonghua Yi Xue Za Zhi. 2021 Sep 21;101(35):2745-2747. doi: 10.3760/cma.j.cn112137-20201218-03388.
Benzodiazepines have been on the market for more than half a century and are widely used in clinical practice. Their use in many countries has been limited in recent decades due to drug dependence and dose tolerance in some patients. Currently, benzodiazepines are still effective in treating many mental disorders, but some patients and doctors refuse to use them for fear of drug dependence and dementia caused by long-term use. The author suggests that benzodiazepines should be objectively evaluatedand rationally used.
苯二氮䓬类药物已上市半个多世纪,在临床实践中广泛应用。近几十年来,由于部分患者存在药物依赖性和剂量耐受性,其在许多国家的使用受到限制。目前,苯二氮䓬类药物在治疗多种精神障碍方面仍然有效,但一些患者和医生因担心药物依赖和长期使用导致的痴呆而拒绝使用。作者建议应对苯二氮䓬类药物进行客观评估并合理使用。