Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education.
J Int Med Res. 2021 Sep;49(9):3000605211043412. doi: 10.1177/03000605211043412.
Hirschsprung-associated enterocolitis (HAEC) is a serious and life-threatening condition, and atypical tuberculosis (TB) associated with HAEC is even more serious. A male newborn aged 4 days was diagnosed with Hirschsprung disease and transanal Soave pull-through was performed at 4 months old. Six months later, he suffered from enterocolitis. Although he was treated with multiple broad-spectrum antibiotics for 2 weeks, he developed a fever without any other symptoms for TB infection. We found numerous, bilateral, uniformly distributed, small pulmonary nodules in the lower lobes in an abdominal radiograph by chance. He was then discharged with complete resolution of all symptoms after anti-TB therapy. Early diagnosis and treatment of TB can effectively improve the prognosis of children with HAEC.
先天性巨结肠相关性肠炎（HAEC）是一种严重且危及生命的疾病，而与 HAEC 相关的不典型结核病（TB）则更为严重。一名 4 天大的男性新生儿被诊断为先天性巨结肠病，并在 4 个月大时进行了经肛门 Soave 拖出术。6 个月后，他患上了肠炎。尽管他接受了 2 周的多种广谱抗生素治疗，但他出现了发热，而没有任何其他结核病感染的症状。我们偶然在腹部 X 光片中发现，他的下叶有许多双侧、均匀分布、小的肺结节。在接受抗结核治疗后，他所有的症状完全缓解，随后出院。早期诊断和治疗结核病可以有效改善 HAEC 患儿的预后。
