Nguyen-Soenen Jérôme, Jourdain Maud, Fournier Jean-Pascal
Université de Nantes, Nantes, France.
Ann Pharmacother. 2022 Jul;56(7):800-808. doi: 10.1177/10600280211046630. Epub 2021 Sep 23.
Proton pump inhibitor (PPI) deprescribing is recommended in case of inappropriate use. Patient education materials are key elements in the deprescribing process.
The study objective was to develop patient education material for PPI deprescribing in primary care in France.
This was a mixed-methods study involving (1) a literature review of the existing patient education materials on PPI deprescribing to identify key points to optimize the layout and content of the document; (2) development of a first version of the brochure by a pluri-professional steering group, following the national reference methodology of the French National Authority for Health (Haute Autorité de Santé) and iterative modifications of the patient brochure; (3) assessment of the content and understandability of the brochure by questionnaires followed by semistructured interviews with target patients; and (4) iterative brochure readability assessment with the Flesch reading ease tool.
The final patient education material is a double-sided A3 brochure-that is, 4 A4 pages. The first round of user testing by questionnaire (n = 14 patients) led to modifications to improve the document understandability, validated in the second round of user testing by questionnaire (n = 10 patients). The semistructured interviews (n = 10 patients) highlighted an adequate comprehension, whereas actionability required some minor modifications. The readability test score of the final education brochure was 59.4.
This patient education brochure for PPI deprescribing is targeted to patients in primary care. Its impact on PPI deprescribing will be assessed in a population-based pragmatic trial in primary care.
在不当使用质子泵抑制剂（PPI）的情况下，建议减少其使用。患者教育材料是减少用药过程中的关键要素。
本研究的目的是为法国初级医疗保健中PPI的减药制定患者教育材料。
这是一项混合方法研究，包括：（1）对现有的关于PPI减药的患者教育材料进行文献综述，以确定优化文档布局和内容的关键点；（2）由多专业指导小组按照法国国家卫生管理局（Haute Autorité de Santé）的国家参考方法制定手册的第一版，并对患者手册进行迭代修改；（3）通过问卷调查评估手册的内容和可理解性，随后对目标患者进行半结构化访谈；（4）使用弗莱什易读性工具对手册进行迭代可读性评估。
最终的患者教育材料是一份双面A3手册，即4页A4纸。第一轮通过问卷调查进行的用户测试（n = 14名患者）促使对手册进行修改以提高其可理解性，第二轮通过问卷调查进行的用户测试（n = 10名患者）验证了这些修改。半结构化访谈（n = 10名患者）表明理解程度足够，但可操作性方面需要一些小的修改。最终教育手册的可读性测试分数为59.4。
这份用于PPI减药的患者教育手册针对初级医疗保健中的患者。其对PPI减药的影响将在一项基于初级医疗保健人群的实用试验中进行评估。
