R&D Laboratory, Diagnosticum Zrt., Attila út 126, Budapest, 1047, Hungary.
MTA-ELTE Immunology Research Group, Eötvös Loránd University, Pázmány P. s. 1/C, Budapest, H-1117, Hungary.
Biol Futur. 2021 Mar;72(1):37-44. doi: 10.1007/s42977-020-00061-1. Epub 2021 Feb 20.
Determination of the presence of antibodies against infectious agents, self-antigens, allogeneic antigens and environmental antigens is the goal of medical serology. Along with the standardization of these tests the community also started to use the expression "quantitative serology," referring to the fact that arbitrary units are used for the expression of results. In this review I will argue against the use of the term quantitative serology for current tests. Because each test and each antibody isotype determination uses its own references, the term semiquantitative better describes these methods. The introduction of really quantitative serology could both benefit from and drive forward systems immunological approach to immunity.
确定针对传染性病原体、自身抗原、同种抗原和环境抗原的抗体的存在，是医学血清学的目标。随着这些测试的标准化，人们也开始使用“定量血清学”这一表述，指的是结果的表达使用任意单位。在这篇综述中，我将反对当前测试中使用“定量血清学”这一术语。因为每种测试和每种抗体同种型测定都使用自己的参考值，所以“半定量”这一术语更能描述这些方法。真正的定量血清学的引入既能受益于，也能推动系统免疫方法在免疫领域的发展。
