Natural Product and Synthetic Chemistry Lab, Department of Chemistry, Government College University Faisalabad, Pakistan.
Department of Botany, Government College University Faisalabad, Pakistan.
Comb Chem High Throughput Screen. 2022;25(7):1187-1199. doi: 10.2174/1386207325666210923120957.
Fagonia arabica, belonging to family Zygophyllaceae, is a medicinal plant widely distributed in the desert areas of the world, including Saudi Arabia, Pakistan, India and South Africa. The present review aims to explore the published information on the traditional uses, ethnobotanical knowledge, phytochemistry and various biological activities like antioxidant, antimicrobial, thrombolytic activities and anticoagulant effects of Fagonia arabica with critical analysis on the gaps and future perspectives.
A literature survey was performed by searching the digital libraries and the scientific databases including Scopus, Google Scholar, SciFinder, ACS, Web of Science and published books.
Fagonia arabica plant has been reported to have a wide range of traditional uses in sore mouth, smallpox, hematological, neurological, endocrinological, inflammatory, cooling agent in stomatitis, vertigo and endothermic reaction in the body. Several bioactive constituents, including glycosides, flavonoids, terpenoids, saponins, alkaloids and trace elements, were recorded from Fagonia arabica plant. The isolation and identification of two flavonoid glycosides (kaempferol-7- O-rhamnoside and acacetin-7-O-rhamnoside) were also reported. Fagonia arabica has been studied for its wide range of biological activities, which include antioxidant, antimicrobial, cardioprotective and anticoagulant.
It is apparent from the literature that Fagonia arabica plant possesses a wide range of medicinal and pharmacological uses and has been studied for its various pharmacological activities and medicinal applications. Critical analysis reveals that the plant has huge potential for pharmaceutical and pharmacological applications.
Arabica Fagonia 属于蒺藜科,是一种药用植物,广泛分布于世界各地的沙漠地区,包括沙特阿拉伯、巴基斯坦、印度和南非。本综述旨在探讨已发表的关于 Arabica Fagonia 的传统用途、民族植物学知识、植物化学和各种生物活性的信息,如抗氧化、抗菌、溶栓和抗凝作用,并对其差距和未来前景进行批判性分析。
通过搜索数字图书馆和科学数据库(包括 Scopus、Google Scholar、SciFinder、ACS、Web of Science 和已出版的书籍)进行文献调查。
Arabica Fagonia 植物被报道具有广泛的传统用途,可用于治疗口疮、天花、血液学、神经病学、内分泌学、炎症、口腔炎中的清凉剂、眩晕和体内吸热反应。从 Arabica Fagonia 植物中记录了几种生物活性成分,包括糖苷、类黄酮、萜类、皂苷、生物碱和微量元素。还报道了两种黄酮糖苷(山奈酚-7-O-鼠李糖苷和芹菜素-7-O-鼠李糖苷)的分离和鉴定。Arabica Fagonia 因其广泛的生物活性而受到研究,包括抗氧化、抗菌、心脏保护和抗凝作用。
从文献中可以明显看出,Arabica Fagonia 植物具有广泛的药用和药理学用途,并因其各种药理学活性和药用应用而受到研究。批判性分析表明,该植物具有巨大的药物和药理学应用潜力。