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通过调节可改变的风险因素管理2型糖尿病:预防脑血管并发症的未来路线图。

Management of Type II Diabetes by Modulating the Modifiable Risk Factors: A Future Roadmap for Prevention of Cerebrovascular Complications.

作者信息

Sharma Kanupriya, Battu Priya, Anand Akshay, Nagarathna Raghuram, Kaur Navneet, Malik Neeru, Singh Amit, Nagendra Hongasandhra R

机构信息

Department of Neurology, Neuroscience Research Lab, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

These contributed equally to this work.

出版信息

Ann Neurosci. 2020 Jul;27(3-4):266-272. doi: 10.1177/09727531211000041. Epub 2021 May 28.

DOI:10.1177/09727531211000041
PMID:34556967
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8455006/
Abstract

BACKGROUND

Indian Diabetes Risk Score (IDRS) is a screening tool for quantifying the risk of diabetes mellitus (DM) development in the Indian population. The present study has evaluated the level of risk of developing DM in Chandigarh and Panchkula based on the IDRS score.

METHODS

As a part of a national diabetes control trial funded by the Ministry of Health and Family Welfare (MoHFW) and the Ministry of AYUSH, Government of India, 1,916 participants from the Chandigarh and Panchkula regions were assessed for the risk of developing DM. Risk assessment was done on the basis of the IDRS score which includes age, family history, waist circumference, and physical activity as its contributing factors. Participants with an IDRS score <30 were in the low-risk category, those with 30 to 50 were in the moderate-risk category, and those with >60 were in the high-risk category for DM.

RESULTS

Out of the 1,916 screened respondents (59.86% females and 40.14% males), 894 participants (46.65%) were at a high risk for DM (IDRS >60), 764 (39.87%) were at a moderate risk (IDRS = 30-60), and 258 (13.46%) were at a low risk (IDRS <30). Waist circumference contributed to 35.90% of the high-risk category followed by age (19.67%) and physical activity (11.67%). Age and waist circumference also showed a strong correlation with the total IDRS score.

CONCLUSION

The Chandigarh and Panchkula population showed a high tendency to develop DM based on the IDRS score. Modifiable risk factors such as waist circumference and physical activity were the major contributing factors. Apart from the modifiable risk factors, age was also another major contributing risk factor. Based on these outcomes, lifestyle modifications like yoga and exercise can be proposed for this population as a preventive approach to reduce the risk of developing DM and other associated cerebrovascular complications.

摘要

背景

印度糖尿病风险评分(IDRS)是一种用于量化印度人群患糖尿病(DM)风险的筛查工具。本研究基于IDRS评分评估了昌迪加尔和潘切库拉地区患DM的风险水平。

方法

作为由印度卫生与家庭福利部(MoHFW)和印度政府阿育吠陀部资助的一项全国糖尿病控制试验的一部分,对来自昌迪加尔和潘切库拉地区的1916名参与者进行了患DM风险评估。风险评估基于IDRS评分进行,该评分将年龄、家族史、腰围和身体活动作为影响因素。IDRS评分<30的参与者属于低风险类别,30至50的属于中度风险类别,>60的属于DM高风险类别。

结果

在1916名接受筛查的受访者中(女性占59.86%,男性占40.14%),894名参与者(46.65%)患DM风险高(IDRS>60),764名(39.87%)属于中度风险(IDRS = 30 - 60),258名(13.46%)属于低风险(IDRS<30)。腰围对高风险类别的贡献率为35.90%,其次是年龄(19.67%)和身体活动(11.67%)。年龄和腰围与IDRS总分也显示出很强的相关性。

结论

基于IDRS评分,昌迪加尔和潘切库拉人群显示出患DM的高倾向。腰围和身体活动等可改变的风险因素是主要促成因素。除了可改变的风险因素外,年龄也是另一个主要的促成风险因素。基于这些结果,可以建议该人群进行瑜伽和锻炼等生活方式改变,作为降低患DM和其他相关脑血管并发症风险的预防方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ac7/8455006/718d2b6dd007/10.1177_09727531211000041-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ac7/8455006/718d2b6dd007/10.1177_09727531211000041-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ac7/8455006/718d2b6dd007/10.1177_09727531211000041-fig1.jpg

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