Swami Vivekananda Yoga Research Foundation, Bengaluru, India.
Neuroscience Research Lab, Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Diabetes Res Clin Pract. 2020 Apr;162:108088. doi: 10.1016/j.diabres.2020.108088. Epub 2020 Feb 19.
To screen the Indian population for Type 2 Diabetes Mellitus (DM) based on Indian Diabetes Risk Score. Our main question was; Does Indian Diabetic risk score (IDRS) effectively screen diabetic subjects in Indian population?
Multi-centric nationwide screening for DM and its risk in all populous states and Union territories of India in 2017. It is the first pan India DM screening study conducted on 240,000 subjects in a short period of 3 months based on IDRS. This was a stratified translational research study in randomly selected cluster populations from all zones of rural and urban India. Two non-modifiable (age, family history) and two modifiable (waist circumference & physical activity) were used to obtain the score. High, moderate and low risk groups were selected based on scores.
In this study 40.9% subjects were detected to be high risk, known or newly diagnosed DM subjects in urban and rural regions. IDRS could detect 78.1% known diabetic subjects as high risk group. Age group 50-59 (17.4%); 60-69 (22%); 70-79 (22.8%); >80 (19.2%) revealed high percentage of subjects. ROC was found to be 0.763 at CI 95% of 0.761-0.765 with statistical significance of p < 0.0001. At >50 cut off, youden index showed the sensitivity of 78.05 and specificity of 62.68. Regression analysis revealed that IDRS and Diabetes are significantly positively associated.
Data reveals that IDRS is a good indicator of high risk diabetic subjects.
根据印度糖尿病风险评分（IDRS）筛选印度 2 型糖尿病（DM）人群。我们的主要问题是：IDRS 是否能有效地筛选印度人群中的糖尿病患者？
2017 年在印度所有人口众多的邦和联邦属地进行了多中心全国性 DM 及其风险筛查。这是一项基于 IDRS 在 3 个月内对 24 万名受试者进行的首次全印度 DM 筛查研究。这是一项在印度农村和城市各地区随机选择聚类人群进行的分层转化研究。使用了两个不可改变的（年龄、家族史）和两个可改变的（腰围和体力活动）因素来获得分数。根据分数选择高、中、低风险组。
在这项研究中，40.9%的城市和农村地区的受试者被检测为高风险、已知或新诊断的 DM 患者。IDRS 可以检测到 78.1%的已知糖尿病患者为高风险组。年龄组 50-59 岁（17.4%）、60-69 岁（22%）、70-79 岁（22.8%）、>80 岁（19.2%）显示出高比例的受试者。ROC 在 95%置信区间（CI）为 0.761-0.765 时为 0.763，具有统计学意义（p<0.0001）。在>50 个截止值时，Youden 指数显示出 78.05%的敏感性和 62.68%的特异性。回归分析显示，IDRS 和糖尿病呈显著正相关。
数据表明，IDRS 是一个很好的糖尿病高危患者指标。
