Fowler J F, Parsley W M, Cotter P G
Arch Dermatol. 1986 Jan;122(1):80-1.
Urticaria pigmentosa, characterized by cutaneous mast cell proliferation, usually occurs sporadically in childhood and resolves over a period. Rarely is the condition seen in two or more members of a family. We encountered a family in which urticaria pigmentosa occurred in four members of two generations. Skin findings were similar in all four. No systemic manifestations other than occasional flushing episodes were noted in any of the affected individuals. HLA typing was performed, but no significant correlation between affected and unaffected individuals was seen. In a review of a number of previously reported cases, we found a slight female preponderance.
色素性荨麻疹以皮肤肥大细胞增殖为特征，通常在儿童期散发出现，并在一段时间后消退。这种疾病很少在一个家族的两个或更多成员中出现。我们遇到了一个家族，其中两代四人都患有色素性荨麻疹。这四人的皮肤表现相似。在任何受影响的个体中，除了偶尔的潮红发作外，没有发现其他全身表现。进行了HLA分型，但未发现患病个体与未患病个体之间存在显著相关性。在回顾许多先前报道的病例时，我们发现女性略占多数。
