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基于基础胰岛素治疗的护士主导在线教育方案在糖尿病患者中的效果:一项准实验研究。

Effectiveness of a nurse-led online educational programme based on basic insulin therapy in patients with diabetes mellitus: A quasi-experimental trial.

机构信息

Department of Endocrinology, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, No.7 Weiwu Street, Zhengzhou, 450000, China.

出版信息

J Clin Nurs. 2022 Aug;31(15-16):2227-2239. doi: 10.1111/jocn.16041. Epub 2021 Sep 23.

Abstract

AIMS AND OBJECTIVES

To evaluate the effectiveness of a nurse-led online educational programme based on patients with diabetes mellitus treated with initial basal insulin therapy.

BACKGROUND

Patients with type 2 diabetes mellitus (T2DM) need to be treated with insulin to control hyperglycaemia and reduce the risk of diabetic complications when oral hypoglycaemic drugs are not effective or contraindicated. Current practices emphasise the leading role of nurses in patients treated with initial basal insulin therapy after discharge. The introduction of nurse-led online education within this area is a relatively new programme.

DESIGN

This study was a quasi-experimental, nonequivalent, two-group, comparison group design.

METHODS

The study selected 800 patients with T2DM hospitalised in the Department of Endocrinology at a Chinese hospital from July 2018 to June 2020 who were initially treated with insulin. According to the time sequence, 400 patients from July 2018 to June 2019 were divided into the control group and 400 patients from July 2019 to June 2020 into the intervention group. The control group received routine health education and doctor-led follow-up based on routine health education. The intervention group received systematic health education and online insulin injection activities led by nurses. The effects were evaluated after 3 and 6 months of intervention. The TREND checklist was followed to ensure rigour in the study.

RESULTS

In total, 339 patients were enrolled in the intervention group and 333 patients within the control group. According to the analysis, 3 months after the intervention, the compliance rate of fasting blood glucose (FBG) (rate difference: 0.078, 95% CI: 0.006-1.150, p < .05) and HbA1c (%) (rate difference: 0.070, 95% CI: 0.001-0.137, p < .05) between the intervention and control groups were statistically significant; 6 months after the intervention, the compliance rate of FBG (rate difference: 0.077, 95% CI: 0.007-0.14, p < .05) and HbA1c (%) (rate difference: 0.106, 95% CI: 0.324-0.180, p < .01) between the intervention and the control groups were statistically significant. The total score of the 'My Opinion on Insulin' scale in the intervention group was (80.18 ± 6.68), and in the control group was (71.15 ± 8.17), there was a significant difference in the scale between the two groups (mean difference: 9.03, 95% CI: 7.900-10.160, p < .01). Through a multivariable regression model, in order to correct the important baseline characteristics, the daily insulin dosage, and the total score of the 'My Opinion on Insulin' scale after 6 months of intervention were independent risk factors for the two intervention methods in diabetic patients treated with initial basal insulin therapy (p < .05).

CONCLUSIONS

A nurse-led online programme was feasible and effective for patients with diabetes mellitus treated with initial basal insulin therapy. This programme could effectively be used to reduce the patient's daily insulin dose, as well as improve the patients' compliance using insulin therapy.

RELEVANCE TO CLINICAL PRACTICE

Nurse-led online education has a role in implementing a safe, standardised, and sustained approach to patients with diabetes mellitus treated with initial basal insulin therapy during follow-up after discharge.

摘要

目的与目标

评估基于接受初始基础胰岛素治疗的糖尿病患者的护士主导的在线教育计划的有效性。

背景

当口服降糖药无效或禁忌时,2 型糖尿病(T2DM)患者需要使用胰岛素来控制高血糖并降低糖尿病并发症的风险。目前的实践强调在患者出院后接受初始基础胰岛素治疗时护士的主导作用。在该领域引入护士主导的在线教育是一个相对较新的方案。

设计

这是一项准实验、非等效、两组、对照组设计的研究。

方法

该研究选择了 2018 年 7 月至 2020 年 6 月期间在中国医院内分泌科住院的 800 名接受初始胰岛素治疗的 T2DM 患者。根据时间顺序,2018 年 7 月至 2019 年 6 月的 400 名患者分为对照组,2019 年 7 月至 2020 年 6 月的 400 名患者分为干预组。对照组接受常规健康教育和医生主导的随访,基于常规健康教育。干预组接受系统的健康教育和护士主导的在线胰岛素注射活动。在干预后 3 个月和 6 个月评估效果。遵循 TREND 清单以确保研究的严谨性。

结果

共有 339 名患者被纳入干预组,333 名患者被纳入对照组。根据分析,干预 3 个月后,空腹血糖(FBG)的依从率(差异率:0.078,95%置信区间:0.006-1.150,p<.05)和糖化血红蛋白(HbA1c)%(差异率:0.070,95%置信区间:0.001-0.137,p<.05)在干预组和对照组之间具有统计学意义;干预 6 个月后,FBG 的依从率(差异率:0.077,95%置信区间:0.007-0.14,p<.05)和 HbA1c%(差异率:0.106,95%置信区间:0.324-0.180,p<.01)在干预组和对照组之间具有统计学意义。干预组“对胰岛素的看法”量表总分为(80.18±6.68),对照组为(71.15±8.17),两组间量表存在显著差异(平均差异:9.03,95%置信区间:7.900-10.160,p<.01)。通过多变量回归模型,为了纠正重要的基线特征,干预后 6 个月的每日胰岛素剂量和“对胰岛素的看法”量表总分是接受初始基础胰岛素治疗的糖尿病患者两种干预方法的独立危险因素(p<.05)。

结论

护士主导的在线计划对接受初始基础胰岛素治疗的糖尿病患者是可行且有效的。该方案可有效降低患者的每日胰岛素剂量,并提高患者对胰岛素治疗的依从性。

临床意义

护士主导的在线教育在实施安全、规范和持续的方法方面对接受初始基础胰岛素治疗的糖尿病患者具有作用,以在出院后进行随访。

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