Tromp J A, Jansen J, Pilot T
J Clin Periodontol. 1986 Feb;13(2):164-8. doi: 10.1111/j.1600-051x.1986.tb01451.x.
The aim of this experiment was to study clinical parameters when 3 different frequencies of plaque removal were applied to healthy gingivae in the beagle dog model. The maxillary first, second and third premolars of 12 beagle dogs, at the start of the experiment 2 years of age, were, after a thorough cleaning, submitted to daily plaque removal during a pre-experimental period of 8 weeks. At the start of the experiment, the dogs were distributed into 3 groups of 4 dogs each: one group was brushed 7 times a week, a second group was brushed 3 times a week and another group was brushed only once a week. Brushing was executed over a period of 24 weeks, on the right sides of the upper jaws. The left upper jaws served as controls. At regular intervals, the plaque index, the gingival index and probing depths were assessed. A "brushing effect" was calculated for each dog, to include information on all within-dog and between dog variations. Comparison of brushing effects revealed that in this experimental model, plaque removal with a frequency of 3 times a week was sufficient to preserve gingival health, whereas tooth brushing once a week resulted in gingival inflammation. Therefore it can be concluded that 3 times a week is the critical brushing frequency in the beagle dog model with healthy gingiva at baseline.
本实验的目的是在比格犬模型中，研究对健康牙龈采用3种不同频率清除牙菌斑时的临床参数。12只2岁的比格犬，在实验开始时，其上颌第一、第二和第三前磨牙在彻底清洁后，在为期8周的实验前期进行每日牙菌斑清除。实验开始时，将这些犬分为3组，每组4只：一组每周刷牙7次，第二组每周刷牙3次，另一组每周仅刷牙1次。刷牙在上颌右侧进行，为期24周。左上颌作为对照。定期评估牙菌斑指数、牙龈指数和探诊深度。为每只犬计算“刷牙效果”，以纳入所有犬内和犬间变异的信息。刷牙效果的比较显示，在该实验模型中，每周3次的牙菌斑清除频率足以保持牙龈健康，而每周刷牙1次会导致牙龈炎症。因此可以得出结论，在基线牙龈健康的比格犬模型中，每周3次是关键的刷牙频率。
