Department of Bioengineering, Stanford University, Stanford, CA 94305, USA; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford, CA 94305, USA.
Cell. 2021 Oct 14;184(21):5279-5285. doi: 10.1016/j.cell.2021.08.018. Epub 2021 Sep 24.
On the occasion of the 2021 Lasker Basic Medical Research Award to Karl Deisseroth, Peter Hegemann, and Dieter Oesterhelt (for "the discovery of light-sensitive microbial proteins that can activate or deactivate individual brain cells-leading to the development of optogenetics and revolutionizing neuroscience"), Deisseroth reflects on this international collaboration, his basic mechanistic and structural discoveries regarding microbial channels that transduce photons into ion current, the causal exploration of brain cell function, and the pressing mysteries of psychiatry.
在 2021 年拉斯克基础医学研究奖授予卡尔·戴瑟罗斯（Karl Deisseroth）、彼得·黑格曼（Peter Hegemann）和迪特尔·奥斯特黑尔特（Dieter Oesterhelt）（“发现了感光微生物蛋白，可激活或失活单个脑细胞——促成了光遗传学的发展并彻底改变了神经科学”）之际，戴瑟罗斯反思了这项国际合作，他在微生物通道方面的基本机械和结构发现，这些通道将光子转化为离子流，对脑细胞功能的因果探索，以及精神病学的紧迫谜团。
Zotero 插件