Department of Oral Surgery and Pathology, School of Dentistry Universidade Federal de Minas Gerais (UFMG) Av. Presidente Antônio Carlos, 6627 CEP 31270-901, Pampulha, Belo Horizonte, MG, Brazil
Med Oral Patol Oral Cir Bucal. 2022 Jan 1;27(1):e35-e41. doi: 10.4317/medoral.24870.
Angina bullosa haemorrhagica (ABH) is characterized by the recurrent appearance of blood blisters on the oral mucosa, mainly in adults' soft palate. In general, the blisters rupture spontaneously, lacking the necessity for biopsy. We report the clinical features of 23 ABH cases, emphasizing the clinical behavior and the management of these conditions.
A retrospective descriptive cross-sectional study was performed. A total of 12,727 clinical records of oral and maxillofacial lesions from four dental services in Brazil were analyzed. Clinical data were collected from the clinical records and evaluated.
The series comprised 12 males (52.2%) and 11 females (47.8%), with a mean age of 56.8 ± 14.6 years (ranging: 24-82 years) and a 1.1:1 male-to-female ratio. Most of the lesions affected the soft palate (n = 15, 65.2%). Clinically, the lesions presented mainly as an asymptomatic (n = 17, 73.9%) blood-filled blister that ruptured after a few minutes or hours, leaving an erosion. The masticatory trauma was the most frequent triggering event. No patient had coagulation disorders. A biopsy was performed in only four cases (17.4%). Treatment was symptomatic with a favorable outcome.
ABH is still poorly documented in the literature, and its etiology remains uncertain. ABH mainly affects the soft palate of elderly adults and has a favorable evolution in a few days. The therapeutic approach is often focused only on the relief of symptoms. However, it can share some clinical features with more serious diseases. Therefore, clinicians must recognize these lesions to avoid misdiagnosis.
出血性大疱性牙龈（ABH）的特征是口腔黏膜上反复出现血疱，主要发生在成人的软腭。通常，疱壁会自行破裂，无需进行活检。我们报告了 23 例 ABH 病例的临床特征，重点介绍了这些病症的临床行为和处理方法。
进行了回顾性描述性横断面研究。分析了来自巴西四个牙科服务机构的 12727 例口腔和颌面病变的临床记录。从临床记录中收集并评估了临床数据。
该系列包括 12 名男性（52.2%）和 11 名女性（47.8%），平均年龄为 56.8±14.6 岁（范围：24-82 岁），男女比例为 1.1:1。大多数病变影响软腭（n=15，65.2%）。临床上，病变主要表现为无症状（n=17，73.9%）、充满血液的水疱，数分钟或数小时后破裂，留下糜烂。咀嚼创伤是最常见的触发事件。没有患者存在凝血障碍。仅有 4 例（17.4%）进行了活检。治疗方法为对症治疗，预后良好。
ABH 在文献中记录较少，其病因仍不确定。ABH 主要影响老年成人的软腭，数天后即可痊愈。治疗方法通常仅侧重于缓解症状。然而，它可能与更严重的疾病有一些共同的临床特征。因此，临床医生必须识别这些病变以避免误诊。
