斑秃患者的心电图表现
Electrocardiogram Findings in Patients with Alopecia Areata.
作者信息
Peterson Danielle, Wambier Carlos, Dai Feng, Lampert Rachel, Ahmad Tariq, Yale Katerina L, Mesinkovska Natasha A, King Brett
机构信息
Department of Dermatology, Yale School of Medicine, New Haven, CT, USA.
Department of Dermatology, Brown University, Providence, RI, USA.
出版信息
Dermatol Ther (Heidelb). 2021 Dec;11(6):2217-2223. doi: 10.1007/s13555-021-00614-9. Epub 2021 Sep 26.
INTRODUCTION
While autoimmune comorbidities are common in alopecia areata, little is known about comorbid cardiovascular disease. The purpose of this study was to evaluate the incidence of bradyarrhythmia in patients with alopecia areata.
METHODS
Retrospective review of electrocardiograms of 124 patients with [Formula: see text] 50% scalp hair loss (severe alopecia areata) was conducted and compared to National Health and Nutrition Examination Survey (NHANES) data.
RESULTS
The prevalence of bradycardia in females with alopecia areata was 24.3% (95% CI, 14.5-34.1%) and in those age 40 years or older was 40.8% (95% CI, 22.2-53.5%) compared to 19.5% in the NHANES III population. The prevalence of bradycardia in males with alopecia areata was 36.0% (95% CI, 22.7-49.3%) and in those age 40 years or older was 50.0% (95% CI, 21.7-78.3%) compared to 26.9% in the NHANES III population.
CONCLUSION
The potential association between bradycardia and alopecia areata merits further investigation.
引言
虽然自身免疫性合并症在斑秃中很常见，但对于合并的心血管疾病却知之甚少。本研究的目的是评估斑秃患者中缓慢性心律失常的发生率。
方法
对124例头皮脱发达50%（重度斑秃）患者的心电图进行回顾性分析，并与美国国家健康与营养检查调查（NHANES）数据进行比较。
结果
斑秃女性患者心动过缓的患病率为24.3%（95%可信区间，14.5 - 34.1%），40岁及以上患者为40.8%（95%可信区间，22.2 - 53.5%），而NHANES III人群中的患病率为19.5%。斑秃男性患者心动过缓的患病率为36.0%（95%可信区间，22.7 - 49.3%），40岁及以上患者为50.0%（95%可信区间，21.7 - 78.3%），而NHANES III人群中的患病率为26.9%。
结论
心动过缓与斑秃之间的潜在关联值得进一步研究。
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