中国 30 多年来阿尔茨海默病和其他类型痴呆症死亡率趋势

Trends in Mortality Rates for Alzheimer's Disease and Other Dementias Over 30 Years in China.

机构信息

Evidence-Based Research Center of Social Science & Health, School of Public Affairs, 12436Nanjing University of Science & Technology, Nanjing, China.

School of Health Economics and Management, 210046Nanjing University of Chinese Medicine, Nanjing, China.

出版信息

Am J Alzheimers Dis Other Demen. 2021 Jan-Dec;36:15333175211044884. doi: 10.1177/15333175211044884.

OBJECTIVE

This study examines trends in the mortality of Alzheimer's disease and other dementias in China from 1990 to 2019.

METHODS

The data were drawn from the Global Burden of Disease Study 2019 (GBD 2019), and an age-period-cohort model was used for analysis.

RESULTS

The net drift was .152% (95% confidence interval [CI]: .069%, .235%) per year for men ( < .05) and .024% (95% CI: -.078%, .126%) per year for women. The local drift values were below 0 in both genders for people aged 45-54 years ( < .05), and above 0 for males aged 60-94 years and females aged 60-79 years ( < .05). In the same birth cohort, the risk of mortality of Alzheimer's disease and other dementias exponentially increases with age for both genders.

CONCLUSION

More rapid and effective efforts are needed to mitigate the substantial impact of Alzheimer's and other dementias on the health of China's elderly.

目的

本研究旨在探讨 1990 年至 2019 年中国阿尔茨海默病和其他类型痴呆症的死亡率趋势。

方法

数据来自 2019 年全球疾病负担研究（GBD 2019），并采用年龄-时期-队列模型进行分析。

结果

男性每年的净漂移率为 0.152%（95%置信区间：0.069%，0.235%）（<0.05），女性每年的净漂移率为 0.024%（95%置信区间：-0.078%，0.126%）。对于 45-54 岁的人群，两性的局部漂移值均低于 0（<0.05），而对于 60-94 岁的男性和 60-79 岁的女性，局部漂移值均高于 0（<0.05）。在同一出生队列中，两性的阿尔茨海默病和其他类型痴呆症的死亡率随年龄呈指数增长。