School of International Pharmaceutical Business, China Pharmaceutical University, Nanjing, Jiangsu, China.
The Research Center of National Drug Policy and Ecosystem, Nanjing, Jiangsu, China.
Front Public Health. 2023 Apr 27;11:1101089. doi: 10.3389/fpubh.2023.1101089. eCollection 2023.
Dementia is more prevalent in women than in men across the world, and sex differences are reflected in the burden of dementia borne by women and men. However, a few studies have specifically analyzed the disease burden of dementia in Chinese women.
This article aims to raise awareness of Chinese females with dementia (CFWD), outline an effective response to future trends in China from a female perspective, and provide a reference for the scientific formulation of dementia prevention and treatment policies in China.
In this article, epidemiological data on dementia in Chinese women were obtained from the Global Burden of Disease Study 2019, and three risk factors, namely, smoking, a high body mass index, and a high fasting plasma glucose, were selected for the analysis. This article also predicted the burden of dementia in Chinese women in the next 25 years.
The prevalence of dementia, mortality, and disability-adjusted life year rates increased with age in CFWD in 2019. All three risk factors provided by the Global Burden of Disease Study 2019 showed positive correlations for the effect of disability-adjusted life years (DALYs) rates on CFWD. Among them, a high body mass index had the greatest effect (8%) and smoking had the smallest effect (6.4%). Over the next 25 years, the number of CFWD and its prevalence are expected to be on the rise, while mortality is expected to remain relatively stable and decline slightly, but deaths from dementia will continue to increase.
The situation arising due to the spread of dementia among Chinese women in the future is going to become a serious issue. To reduce the burden of dementia, the Chinese government should prioritize its prevention and treatment. A multi-dimensional, long-term care system involving families, community, and hospitals should also be established and supported.
在全球范围内，女性患痴呆症的比例高于男性，且这种性别差异体现在女性和男性所承受的痴呆症负担上。然而，仅有少数研究专门分析了中国女性的痴呆症疾病负担。
本文旨在提高对中国女性痴呆症患者（CFWD）的认识，从女性视角出发概述中国未来趋势的有效应对措施，并为中国制定痴呆症防治政策提供参考。
本文从 2019 年全球疾病负担研究中获取了中国女性痴呆症的流行病学数据，并选取了 3 个风险因素，即吸烟、高身体质量指数和高空腹血糖，进行分析。本文还预测了中国女性在未来 25 年的痴呆症负担。
2019 年，CFWD 的痴呆症患病率、死亡率和伤残调整生命年（DALY）率随年龄增长而增加。全球疾病负担研究提供的所有 3 个风险因素均显示与 CFWD 的 DALY 率的影响呈正相关。其中，高身体质量指数的影响最大（8%），吸烟的影响最小（6.4%）。在未来 25 年内，CFWD 的数量及其患病率预计将呈上升趋势，而死亡率预计将保持相对稳定并略有下降，但痴呆症死亡人数将继续增加。
未来中国女性痴呆症的传播情况预计将成为一个严重的问题。为了减轻痴呆症负担，中国政府应优先考虑其预防和治疗。还应建立并支持家庭、社区和医院参与的多维、长期护理系统。
