• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

物质使用障碍的治疗能否开具与所使用物质相同的物质?以注射用阿片类激动剂治疗为例。

Can Treatment for Substance Use Disorder Prescribe the same Substance as that Used? The Case of Injectable Opioid Agonist Treatment.

作者信息

Steel Daniel, Tekin Şerife

出版信息

Kennedy Inst Ethics J. 2021;31(3):271-301. doi: 10.1353/ken.2021.0022.

DOI:10.1353/ken.2021.0022
PMID:34565745
Abstract

This article examines injectable Opioid Agonist Treatment (iOAT), in which patients suffering from long-term, treatment refractory opioid use disorder (OUD) are prescribed injectable diacetylmorphine, the active ingredient of heroin. While iOAT is part of the continuum of care for OUD in some European countries and in some parts of Canada, it is not an available treatment in the United States. We suggest that one reason for this situation is the belief that a genuine treatment for substance use disorder cannot prescribe the same substance as that used. We examine possible rationales for this belief by considering four combinations of views on the constitutive causal basis of substance use disorders and the definition of effective treatment. We show that all but one combination counts iOAT as a genuine treatment and that there are good reasons to reject the one that does not. Specifically, we claim that medical interventions, such as iOAT, that significantly reduce the severity of a disorder deserve to be categorized as effective treatments and regarded as such in practice.

摘要

本文探讨注射用阿片类激动剂治疗(iOAT),即针对患有长期、难治性阿片类物质使用障碍(OUD)的患者,开具注射用二乙酰吗啡(海洛因的活性成分)的治疗方法。虽然iOAT在一些欧洲国家和加拿大的部分地区是OUD连续护理的一部分,但在美国却不是一种可用的治疗方法。我们认为造成这种情况的一个原因是,人们认为针对物质使用障碍的真正治疗方法不能开具与所使用物质相同的物质。我们通过考虑关于物质使用障碍的构成性因果基础和有效治疗定义的四种观点组合,来研究这种观点的可能依据。我们表明,除了一种组合外,其他所有组合都将iOAT视为真正的治疗方法,而且有充分的理由拒绝不这样认为的那种组合。具体而言,我们声称,像iOAT这样能显著降低疾病严重程度的医学干预措施,理应被归类为有效治疗方法,并在实践中如此看待。

相似文献

1
Can Treatment for Substance Use Disorder Prescribe the same Substance as that Used? The Case of Injectable Opioid Agonist Treatment.物质使用障碍的治疗能否开具与所使用物质相同的物质?以注射用阿片类激动剂治疗为例。
Kennedy Inst Ethics J. 2021;31(3):271-301. doi: 10.1353/ken.2021.0022.
2
Take home injectable opioids for opioid use disorder during and after the COVID-19 Pandemic is in urgent need: a case study.COVID-19大流行期间及之后用于阿片类物质使用障碍的居家注射用阿片类药物亟待解决:一项案例研究
Subst Abuse Treat Prev Policy. 2021 Mar 5;16(1):22. doi: 10.1186/s13011-021-00358-x.
3
Exploring Patients' Perceptions on Injectable Opioid Agonist Treatment: Influences on Treatment Initiation and Implications for Practice.探索患者对注射用阿片类激动剂治疗的看法:对治疗启动的影响及实践意义
Eur Addict Res. 2024;30(1):32-42. doi: 10.1159/000535416. Epub 2023 Dec 15.
4
Injectable opioid agonist treatment: An evolutionary concept analysis.注射用阿片类激动剂治疗:一个进化的概念分析。
Res Nurs Health. 2021 Aug;44(4):664-671. doi: 10.1002/nur.22140. Epub 2021 May 16.
5
High Interest in Injectable Opioid Agonist Treatment With Hydromorphone Among Urban Syringe Service Program Participants.城市注射毒品者服务项目参与者对氢吗啡酮类注射阿片激动剂治疗有浓厚兴趣。
Subst Use Addctn J. 2024 Jan;45(1):44-53. doi: 10.1177/29767342231210552.
6
Cost-effectiveness of hydromorphone for severe opioid use disorder: findings from the SALOME randomized clinical trial.氢吗啡酮治疗严重阿片类药物使用障碍的成本效益:来自 SALOME 随机临床试验的结果。
Addiction. 2018 Jul;113(7):1264-1273. doi: 10.1111/add.14171. Epub 2018 Mar 28.
7
Patterns of use and adverse events reported among persons who regularly inject buprenorphine: a systematic review.经常注射丁丙诺啡的人群的使用模式和报告的不良事件:系统评价。
Harm Reduct J. 2022 Oct 13;19(1):113. doi: 10.1186/s12954-022-00695-5.
8
Injectable opioid agonist treatment for opioid use disorder: a national clinical guideline.用于阿片类物质使用障碍的注射用阿片类激动剂治疗:一项国家临床指南。
CMAJ. 2019 Sep 23;191(38):E1049-E1056. doi: 10.1503/cmaj.190344.
9
Perceptions of injectable opioid agonist treatment (iOAT) among people who regularly use opioids in Australia: findings from a cross-sectional study in three Australian cities.在澳大利亚,经常使用阿片类药物的人群对注射用阿片类激动剂治疗(iOAT)的看法:在澳大利亚三个城市进行的横断面研究结果。
Addiction. 2021 Jun;116(6):1482-1494. doi: 10.1111/add.15297. Epub 2020 Nov 23.
10
Service delivery models for injectable opioid agonist treatment in Canada: 2 sequential environmental scans.加拿大注射用阿片类激动剂治疗的服务提供模式:2 项连续的环境扫描。
CMAJ Open. 2021 Feb 23;9(1):E115-E124. doi: 10.9778/cmajo.20200021. Print 2021 Jan-Mar.

引用本文的文献

1
Efficacy of the GLP-1 receptor agonist, semaglutide, in abstinence from illicit and nonprescribed opioids in an outpatient population with treatment-refractory OUD: A randomized, double-blind, placebo-controlled clinical trial protocol.胰高血糖素样肽-1(GLP-1)受体激动剂司美格鲁肽在治疗难治性阿片类物质使用障碍门诊患者中戒除非法和非处方阿片类药物的疗效:一项随机、双盲、安慰剂对照临床试验方案。
Res Sq. 2025 May 26:rs.3.rs-6666196. doi: 10.21203/rs.3.rs-6666196/v1.
2
Challenges for the implementation of injectable opioid agonist treatment: a scoping review.注射用阿片类激动剂治疗实施面临的挑战:一项范围综述
Harm Reduct J. 2024 Dec 4;21(1):217. doi: 10.1186/s12954-024-01102-x.