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经活检证实的猪链球菌相关性感染性肾小球肾炎

Biopsy-proven Streptococcus suis-associated Infectious Glomerulonephritis.

作者信息

Kajitani Hideto, Nishiwaki Hiroki, Ueno Toshiharu, Koiwa Fumihiko, Iwasaki Shigeki, Hirade Satoshi

机构信息

Division of Nephrology, Department of Internal Medicine, Showa University Fujigaoka Hospital, Japan.

Showa University Research Administration Center (SURAC), Showa University, Japan.

出版信息

Intern Med. 2022 Apr 15;61(8):1201-1204. doi: 10.2169/internalmedicine.7823-21. Epub 2021 Sep 25.

Abstract

A 64-year-old Japanese man who worked at a butcher shop was hospitalized for a fever, headache, and deafness. We diagnosed him with sepsis and meningitis caused by Streptococcus suis infection. The patient's renal function declined rapidly, and hemodialysis was performed temporarily. A renal biopsy was performed, and the renal function tended to improve with antimicrobial therapy. This case seemed rather similar to one of staphylococcal-associated nephritis in that it showed mesangial proliferative nephritis with immunoglobulin A deposition, even though the nephritis was caused by streptococci. Similarly, intramembranous electron-dense deposits were characteristic findings. We present new findings of an in vivo renal biopsy in a case of S. suis-associated glomerulonephritis.

摘要

一名在肉店工作的64岁日本男性因发热、头痛和耳聋入院。我们诊断他患有猪链球菌感染引起的败血症和脑膜炎。患者肾功能迅速下降,临时进行了血液透析。进行了肾活检,抗菌治疗后肾功能趋于改善。该病例似乎与葡萄球菌相关性肾炎之一相当相似,尽管肾炎是由链球菌引起的,但它表现为伴有免疫球蛋白A沉积的系膜增生性肾炎。同样,膜内电子致密沉积物是特征性表现。我们报告了一例猪链球菌相关性肾小球肾炎的体内肾活检新发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4e7/9107994/33acd7620ee8/1349-7235-61-1201-g001.jpg

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