Nadal Gerard M
The Coalition on Abortion/Breast Cancer, Staten Island, NY, USA.
Linacre Q. 2021 Aug;88(3):247-253. doi: 10.1177/00243639211014621. Epub 2021 May 28.
There has been a long-simmering disquiet in Catholic circles regarding the use cell lines derived from aborted fetal tissue. This concern has exploded into the public consciousness given the use of questionable cell lines in the development and/or testing of the current COVID-19 vaccines, and the debate within the Church over the permissibility of using these vaccines. The history of cell culture and how the biological community came to rely on HEK293 fetal cell lines is explored, as is the way forward, moving the biotech industry away from ethically problematic cells and toward the development of more ethically sourced cell lines. The role of the Church in leading the way forward and the acceptable use of medicines utilizing HEK293 cell lines are all explored.
在天主教圈子里,对于使用源自堕胎胎儿组织的细胞系一直存在着长期潜伏的不安情绪。鉴于当前新冠疫苗的研发和/或测试中使用了存在问题的细胞系,以及教会内部关于使用这些疫苗是否可允许的辩论,这种担忧已迅速进入公众意识。本文探讨了细胞培养的历史以及生物科学界如何开始依赖人胚肾293(HEK293)胎儿细胞系,还探讨了未来的发展方向,即推动生物技术产业摆脱有伦理问题的细胞,转而开发来源更符合伦理的细胞系。文中还探讨了教会在引领前进道路方面的作用以及使用利用HEK293细胞系的药物的可接受性。