Wang Kun, Jiang Haonan, Zhang Tingran, Yin Lian, Chen Xi, Luo Jiong
Research Centre for Exercise Detoxification, College of Physical Education, Southwest University, Chongqing, China.
Chongqing Drug Rehabilitation Administration, Chongqing, China.
Front Physiol. 2021 Sep 10;12:683942. doi: 10.3389/fphys.2021.683942. eCollection 2021.
Maximum oxygen uptake (VO) is an important respiratory physiological index of the aerobic endurance of the body, especially for special groups such as drug addicts, and it is an important indicator for assessing the cardiopulmonary function and formulating exercise prescriptions. Although the cardiopulmonary exercise test (CPX) is a classic method to directly measure VO, this method is limited by factors such as cumbersome operating procedures and expensive equipment, resulting in its relatively low applicability. Recently, many studies have begun to focus on the estimation of VO in different groups of people, but few studies have focused on drug addicts. Fifteen chemically synthesized drug addicts (such as amphetamines) and Fifteen plant-derived drug addicts (such as heroin) were recruited at the Chongqing Compulsory Isolation and Drug Rehabilitation Center in China. First, the VO of subjects was directly measured through the CPX. Second, after subjects were fully rested, they were required to complete the 30-s high-leg raise, 1,000-m walk, and 3-min step experiment. Finally, SPSS 21.0 software was used to perform the correlation and linear regression analysis to verify the estimated effectiveness. (1) Regardless of chemically synthesized or natural plant-derived drug addicts, the years of drug use and walking time of 1,000 m were significantly negatively correlated with VO (chemically synthesized: < 0.01 and natural plant-derived: < 0.05), the number of 30-s high-leg raises was a significantly positive correlation with VO ( < 0.05 and < 0.01), and the 3-min step index was significantly positively correlated with VO ( < 0.01 and < 0.01). (2) Regression analysis shows that the 30-s high-leg lift, 1,000-m walking, and 3-min step experiment could effectively estimate the VO of chemically synthesized and natural plant-derived drug addicts. (3) Multiple linear regression constructed by the years of drug use combined with the step index has the highest estimated accuracy for the VO of chemically synthesized drug addicts (96.48%), while the unary regression equation established by a single step index has the highest prediction accuracy for the VO of natural plant-derived addicts (94.30%). The indirect measurement method could effectively estimate the VO of drug addicts, but different measurement methods have certain differences in the estimation accuracy of VO of different drug addicts. In the future, the physical characteristics of drug users can be fully considered, combined with more cutting-edge science and technology, to make the estimation accuracy of VO closer to the real level.
最大摄氧量（VO）是身体有氧耐力的一项重要呼吸生理指标，对于吸毒者等特殊群体尤为重要，是评估心肺功能和制定运动处方的重要指标。尽管心肺运动试验（CPX）是直接测量VO的经典方法，但该方法受操作程序繁琐、设备昂贵等因素限制，导致其适用性相对较低。近年来，许多研究开始关注不同人群VO的估计，但针对吸毒者的研究较少。在中国重庆强制隔离戒毒所招募了15名化学合成毒品成瘾者（如苯丙胺类）和15名植物源性毒品成瘾者（如海洛因）。首先，通过CPX直接测量受试者的VO。其次，在受试者充分休息后，要求他们完成30秒高抬腿、1000米步行和3分钟台阶试验。最后，使用SPSS 21.0软件进行相关性和线性回归分析，以验证估计效果。（1）无论是化学合成毒品成瘾者还是天然植物源性毒品成瘾者，吸毒年限和1000米步行时间与VO均呈显著负相关（化学合成毒品成瘾者：<0.01，天然植物源性毒品成瘾者：<0.05），30秒高抬腿次数与VO呈显著正相关（<0.05和<0.01），3分钟台阶指数与VO呈显著正相关（<0.01和<0.01）。（2）回归分析表明，30秒高抬腿、1000米步行和3分钟台阶试验能够有效估计化学合成毒品成瘾者和天然植物源性毒品成瘾者的VO。（3）吸毒年限与台阶指数构建的多元线性回归对化学合成毒品成瘾者VO的估计准确率最高（96.48%），而单一台阶指数建立的一元回归方程对天然植物源性毒品成瘾者VO的预测准确率最高（94.30%）。间接测量方法能够有效估计吸毒者的VO，但不同测量方法对不同吸毒者VO的估计准确率存在一定差异。未来，可充分考虑吸毒者的身体特征，结合更前沿的科学技术，使VO的估计准确率更接近真实水平。
