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疑似ST段抬高型心肌梗死患者延迟首次联系急救服务的相关因素

Correlates of Delayed Initial Contact to Emergency Services among Patients with Suspected ST-Elevation Myocardial Infarction.

作者信息

Lawani Osayi, Gorman Nicholas, Gorman Fiona, Ganim Jiries, Sdringola-Maranga Stefano

机构信息

HCA Houston Healthcare Kingwood, 22999 US Hwy 59 N, Kingwood, TX 77339, USA.

Keck Graduate Institute, 535 Wharton Dr, Claremont, CA 91711, USA.

出版信息

Cardiol Res Pract. 2021 Sep 14;2021:8483817. doi: 10.1155/2021/8483817. eCollection 2021.

Abstract

BACKGROUND

Early diagnosis and treatment of a patient displaying symptoms of myocardial ischemia is paramount in preventing detrimental tissue damage, arrhythmias, and death. Patient-related hospital delay is the greatest considerable cause of total delay in treatment for acute myocardial infarction.

OBJECTIVE

To identify patient characteristics contributing to prehospital delay and ultimately developing health interventions to prevent future delay and improve health outcomes.

METHODS

A retrospective chart review of 287 patients diagnosed with ST-elevation myocardial infarction (STEMI) was evaluated to examine correlates of patient-related delays to care.

RESULTS

Stepwise logistic regression modeling with forward selection (likelihood ratio) was performed to identify predictors of first medical contact (FMC) within 120 minutes of symptom onset and door-to-balloon (DTB) time within 90 minutes. Distance from the hospital, being unmarried, self-medicating, disability, and hemodynamic stability emerged as variables that were found to be predictive of FMC within the first 120 minutes after symptom onset. Similarly, patient characteristics of gender and disability and having an initial nondiagnostic electrocardiogram emerged as significant predictors of DTB within 90 minutes.

CONCLUSIONS

Individual attention to high-risk patients and public education campaigns using printed materials, public lectures, and entertainment mediums are likely needed to disseminate information to improve prevention strategies. Future research should focus on identifying the strengths of prehospital predictors and finding other variables that can be established as forecasters of delay. Interventions to enhance survival in acute STEMI should continue as to provide substantial advances in overall health outcomes.

摘要

背景

对出现心肌缺血症状的患者进行早期诊断和治疗对于预防有害的组织损伤、心律失常和死亡至关重要。与患者相关的医院延误是急性心肌梗死治疗总延误的最主要原因。

目的

确定导致院前延误的患者特征,并最终制定健康干预措施以预防未来的延误并改善健康结果。

方法

对287例诊断为ST段抬高型心肌梗死(STEMI)的患者进行回顾性病历审查,以检查与患者相关的护理延误的相关性。

结果

采用向前选择(似然比)的逐步逻辑回归模型来确定症状发作后120分钟内首次医疗接触(FMC)以及90分钟内门球时间(DTB)的预测因素。离医院的距离、未婚、自行用药、残疾和血流动力学稳定性被发现是症状发作后最初120分钟内FMC的预测变量。同样,性别、残疾以及初始心电图未确诊等患者特征是90分钟内DTB的重要预测因素。

结论

可能需要对高危患者进行个体化关注,并通过印刷材料、公开讲座和娱乐媒体开展公众教育活动,以传播信息,改进预防策略。未来的研究应侧重于确定院前预测因素的优势,并寻找其他可作为延误预测指标的变量。应继续采取干预措施以提高急性STEMI患者的生存率,从而在整体健康结果方面取得重大进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b52/8457972/27077913c5a3/CRP2021-8483817.001.jpg

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