Chattopadhyay Sidhartha, Basu Sagar, Majumdar Kamalesh
Department of Neuro-Medicine, KPC Medical College and Hospital, Kolkata, West Bengal, India.
Department of Radiology, KPC Medical College and Hospital, Kolkata, West Bengal, India.
J Family Med Prim Care. 2021 Jul;10(7):2713-2715. doi: 10.4103/jfmpc.jfmpc_2478_20. Epub 2021 Jul 30.
There are various neurological presentations of covid-19 but here we report a 27-year-old female developed first episode of seizure, 14 days after documented SARS-CoV-2 infection. She had generalized tonic-clonic seizure with multiple injuries. She had no previous or family history of seizure but she had generalized anxiety disorder and was doing well on selective serotonin reuptake inhibitor (SSRI). Electroencephalogram (EEG) showed theta waves background (likely post-ictal discharges). Magnetic resonance Imagining (MRI) Brain showed features of focal cerebritis on both the frontal lobes. She was started with anti-epileptic drug. After 6 weeks, repeat MRI Brain and EEG were completely normal.
新型冠状病毒肺炎(COVID-19)有多种神经学表现,但在此我们报告一名27岁女性,在确诊感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)14天后首次出现癫痫发作。她发生了全身强直阵挛性癫痫发作并伴有多处损伤。她既往及家族均无癫痫病史,但患有广泛性焦虑症,正在服用选择性5-羟色胺再摄取抑制剂(SSRI)且病情稳定。脑电图(EEG)显示θ波背景(可能为发作后放电)。脑部磁共振成像(MRI)显示双侧额叶有局灶性脑炎特征。她开始使用抗癫痫药物治疗。6周后,复查脑部MRI和EEG均完全正常。