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新冠病毒肺炎患者的有创机械通气与临床参数:年龄会是一个因素吗?

Invasive mechanical ventilation and clinical parameters in COVID19 patient: Can age be a factor?

作者信息

Farzan Nina, Vahabi Sepideh, Hashemi Madani Shima Sadat, Farzan Behrooz

机构信息

Department of Emergency Medicine, Clinical Research Development Center, Qom University of Medical Sciences, Qom, Iran.

Department of Anesthesiology, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.

出版信息

Int J Surg Open. 2021 May;32:100344. doi: 10.1016/j.ijso.2021.100344. Epub 2021 Apr 14.

Abstract

BACKGROUND

Severity of corona virus disease 2019 (COVID19) is presented with respiratory distress and requires mechanical ventilation. Advanced age is one of the significant risk factors of the worst prognosis and mortality in this disease. The aim of this study is to investigate the clinical parameter among COVID19 patients under mechanical ventilation in regard to the age groups.

METHOD

In this retrospective study, COVID19 patients under invasive mechanical ventilation at Shahid Beheshti Hospital in Qom were included. The patients were divided in two age groups, those aged ≥50 years and <50 years. Clinical parameter of these patients like blood pressure, heart rate, respiratory rate, oxygen saturation and body temperature were recorded at the time of mechanical ventilation and 24, 48 and 72 h under the mechanical ventilation.

RESULT

A total of 317 patients were included in the study where 214 patients were over the age of 50 years and 98 were under 50 years. The mean age of patients was 59.71 ± 16.46 year. At the start of mechanical ventilation and 24, 48 and 72 h during the ventilation, blood pressure, pulse rate, rate of respiration, oxygen saturation, Glasgow coma scale and temperature were not significantly different at among the two age groups, p > 0.05, respectively.

CONCLUSIONS

The findings of the study indicated that prognosis of COVID19 patients under invasive mechanical ventilation in terms of changes in clinical parameters might not be associated with the age.

摘要

背景

2019年冠状病毒病(COVID-19)的严重程度表现为呼吸窘迫,需要机械通气。高龄是该疾病预后最差和死亡率高的重要危险因素之一。本研究的目的是调查机械通气的COVID-19患者中不同年龄组的临床参数。

方法

在这项回顾性研究中,纳入了库姆市沙希德·贝赫什提医院接受有创机械通气的COVID-19患者。患者被分为两个年龄组,年龄≥50岁和<50岁。在机械通气时以及机械通气后24、48和72小时记录这些患者的临床参数,如血压、心率、呼吸频率、血氧饱和度和体温。

结果

共有317例患者纳入研究,其中214例患者年龄超过50岁,98例患者年龄在50岁以下。患者的平均年龄为59.71±16.46岁。在机械通气开始时以及通气期间的24、48和72小时,两个年龄组之间的血压、脉搏率、呼吸频率、血氧饱和度、格拉斯哥昏迷量表和体温均无显著差异,p>0.05。

结论

研究结果表明,有创机械通气的COVID-19患者在临床参数变化方面的预后可能与年龄无关。

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