Zintgraff J, Prieto M, Peña M, Simoiz F, Rosenblit S, D'Alessandro D, Garces A Fernandez, Di Matteo V, Astesana R, Panno M
Servicio de Bacteriología. Clínica AMEBPBA, CABA, Argentina.
Servicio de Bacteriología Clínica. INEI ANLIS "Dr Carlos G. Malbrán", CABA, Argentina.
Access Microbiol. 2020 Jan 20;2(2):acmi000091. doi: 10.1099/acmi.0.000091. eCollection 2020.
Abscesses caused by the genus spp are relatively rare, accounting for approximately 2 % of all brain abscesses, but with a significantly higher mortality. Special stains of brain abscess material from a 60-year-old man showed Gram-positive branching bacilli and the presence of long, acid-fast branching filamentous bacilli suggesting infection. Presented here is a case of multidisciplinary management of a patient who developed cerebral abscesses by , confirmed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), that was susceptible to trimethoprim/sulfamethoxazole, linezolid, imipenem and not susceptible to minocycline. This case highlights the importance of performing subtyping and antimicrobial testing in order to improve clinical and treatment outcomes due to patterns of antibiotics resistance among species.
由该属物种引起的脓肿相对罕见，约占所有脑脓肿的2%，但死亡率显著更高。一名60岁男性脑脓肿材料的特殊染色显示革兰氏阳性分支杆菌以及存在长的、抗酸分支丝状杆菌，提示感染。本文介绍了一例由该菌引起脑脓肿患者的多学科管理病例，通过基质辅助激光解吸/电离飞行时间质谱（MALDI-TOF MS）确诊，该菌对甲氧苄啶/磺胺甲恶唑、利奈唑胺、亚胺培南敏感，对米诺环素不敏感。该病例强调了进行亚型分类和抗菌测试的重要性，以便因该菌属物种间抗生素耐药模式而改善临床和治疗结果。
