Epidemiology, Public Health and Impact (EPIC) Unit, International Vaccine Institute, Seoul, South Korea.
National Food Institute, WHO Collaborating Centre for Antimicrobial Resistance in Foodborne Pathogens and Genomics and European Union Reference Laboratory for Antimicrobial Resistance, FAO Reference Laboratory for Antimicrobial Resistance, Technical University of Denmark, Kgs. Lyngby, Denmark.
J Antimicrob Chemother. 2021 Dec 24;77(1):268-275. doi: 10.1093/jac/dkab354.
Establishing effective external quality assessment (EQA) programmes is an important element in ensuring the quality of, and building capacity for, antimicrobial resistance (AMR) laboratory surveillance.
To understand the current coverage of, and challenges to participation in, EQAs in National Reference Laboratories (NRLs) across One Health (OH) sectors in Asia.
Current EQA coverage was evaluated through desktop review, online surveys and interviews of both EQA participants and providers. EQA coverage was mapped and summarized by laboratory type and 'readiness' level and identified challenges evaluated qualitatively.
Of the 31 identified NRLs [16 Human Health (HH) and 15 Animal/Food Safety laboratories (A/FS)], 14 HH and 7 A/FS laboratories currently participated in international EQA schemes and several participated in two or more different schemes. Seven laboratories were currently not participating in any EQA scheme and two of these (one HH and one A/FS) do not currently perform microbiology; six HH NRLs provided national EQAs. Of the eight surveyed international EQA providers, three were based in Asia and all offered varying programmes in terms of pathogens, frequency and support mechanisms for reporting and follow-up. Only one provider currently served laboratories across all OH sectors.
The current coverage of EQA programmes for AMR in Asia was heterogeneous across countries but especially across OH sectors. This updated overview of the coverage and challenges associated with participation in, and provision of, EQAs for AMR suggest the benefit and relevance of introducing one comprehensive and high-quality EQA programme across OH sectors in Asia.
建立有效的外部质量评估(EQA)计划是确保抗菌药物耐药性(AMR)实验室监测质量和能力建设的重要组成部分。
了解亚洲跨一个健康(OH)领域的国家参考实验室(NRL)中当前参与 EQA 的覆盖范围和面临的挑战。
通过桌面审查、在线调查和对 EQA 参与者和提供者的访谈评估当前 EQA 的覆盖范围。按实验室类型和“准备”水平对 EQA 覆盖范围进行映射和总结,并定性评估确定面临的挑战。
在所确定的 31 个 NRL 中[16 个人类健康(HH)和 15 个动物/食品安全实验室(A/FS)],有 14 个 HH 和 7 个 A/FS 实验室目前参与了国际 EQA 计划,其中几个实验室参与了两个或更多不同的计划。有 7 个实验室目前不参与任何 EQA 计划,其中两个(一个 HH 和一个 A/FS)目前不进行微生物学检测;有 6 个 HH NRL 提供国家 EQA。在所调查的 8 个国际 EQA 提供者中,有 3 个位于亚洲,均提供不同的计划,涉及病原体、频率以及报告和跟进的支持机制。只有一个提供者目前为所有 OH 部门的实验室提供服务。
亚洲 AMR 的 EQA 计划的当前覆盖范围在国家之间存在差异,但在 OH 部门之间尤其存在差异。对参与和提供 AMR 的 EQA 相关的覆盖范围和挑战的最新概述表明,在亚洲 OH 部门引入一个全面和高质量的 EQA 计划具有益处和相关性。