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低收入和中等收入环境中的抗菌药物耐药性监测——参与全球抗菌药物监测系统(GLASS)的路线图。

AMR Surveillance in low and middle-income settings - A roadmap for participation in the Global Antimicrobial Surveillance System (GLASS).

作者信息

Seale Anna C, Gordon N Claire, Islam Jasmin, Peacock Sharon J, Scott J Anthony G

机构信息

College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.

London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.

出版信息

Wellcome Open Res. 2017 Sep 26;2:92. doi: 10.12688/wellcomeopenres.12527.1. eCollection 2017.

Abstract

Drug-resistant infections caused by bacteria with increasing antimicrobial resistance (AMR) threaten our ability to treat life-threatening conditions. Tackling AMR requires international collaboration and partnership. An early and leading priority to do this is to strengthen AMR surveillance, particularly in low-income countries where the burden of infectious diseases is highest and where data are most limited. The World Health Organization (WHO) has developed the Global AMR Surveillance System (GLASS) as one of a number of measures designed to tackle the problem of AMR, and WHO member states have been encouraged to produce National Action Plans for AMR by 2017. However, low-income countries are unlikely to have the resources or capacity to implement all the components in the GLASS manual. To facilitate their efforts, we developed a guideline that is aligned to the GLASS procedures, but written specifically for implementation in low-income countries. The guideline allows for flexibility across different systems, but has sufficient standardisation of core protocols to ensure that, if followed, data will be valid and comparable. This will ensure that the surveillance programme can provide health intelligence data to inform evidence-based interventions at local, national and international levels.

摘要

抗菌耐药性(AMR)不断增强的细菌所引起的耐药性感染,威胁着我们治疗危及生命疾病的能力。应对抗菌耐药性需要国际合作与伙伴关系。实现这一目标的一项早期且首要的优先任务是加强抗菌耐药性监测,尤其是在传染病负担最重且数据最为有限的低收入国家。世界卫生组织(WHO)已制定了全球抗菌耐药性监测系统(GLASS),作为旨在解决抗菌耐药性问题的多项措施之一,并且鼓励WHO成员国在2017年前制定抗菌耐药性国家行动计划。然而,低收入国家不太可能具备实施GLASS手册中所有内容的资源或能力。为推动其工作,我们制定了一项指南,该指南与GLASS程序保持一致,但专门为在低收入国家实施而编写。该指南允许不同系统之间具有灵活性,但对核心方案有足够的标准化要求,以确保如果遵循这些要求,数据将是有效的且具有可比性。这将确保监测计划能够提供卫生情报数据,为地方、国家和国际层面基于证据的干预措施提供依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b07/5645727/11e0b1b6de92/wellcomeopenres-2-13565-g0000.jpg

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