Leverett D H, McHugh W D, Jensen O E
J Dent Res. 1986 Mar;65(3):424-7. doi: 10.1177/00220345860650031001.
The aim of this study was to compare the effects of daily mouthrinsing with aqueous solutions of 0.05% NaF or 0.1% SnF2 on dental caries and tooth staining. The study population consisted of 437 children, aged from 12 to 15 years at baseline, residing in a non-fluoridated community. By stratified random sampling, the subjects were divided into two groups, one group rinsing daily under supervision for 28 months with the NaF solution and the other with the SnF2 solution. The SnF2 group exhibited four to five times as much extrinsic stain as did the NaF group, although the stains were quite mild and not explicitly distinguishable between groups. There were no statistically significant differences between the two groups in terms of total DMFS. However, the increment of pit and fissure caries was 0.9 surfaces fewer for the SnF2 group (p = 0.04), while the increment of smooth surface caries was 0.6 surfaces fewer for the NaF group (p = 0.04). These data suggest that there may be a difference in mechanism of action between SnF2 and NaF rinses.
本研究的目的是比较每日用0.05%氟化钠(NaF)或0.1%氟化亚锡(SnF₂)水溶液漱口对龋齿和牙齿染色的影响。研究对象为437名儿童,基线年龄为12至15岁,居住在一个未进行氟化处理的社区。通过分层随机抽样,将受试者分为两组,一组在监督下每日用NaF溶液漱口28个月,另一组用SnF₂溶液漱口。SnF₂组的外源性染色是NaF组的四到五倍,不过染色相当轻微,两组之间没有明显区别。两组在总龋失补牙面数(DMFS)方面没有统计学上的显著差异。然而,SnF₂组的窝沟龋增量少0.9个牙面(p = 0.04),而NaF组的平滑面龋增量少0.6个牙面(p = 0.04)。这些数据表明,SnF₂和NaF漱口液的作用机制可能存在差异。