• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Roles of the FGF-FGFR Signaling System in Cancer Development and Inflammation.FGF-FGFR 信号系统在癌症发展和炎症中的作用。
Cells. 2021 Aug 28;10(9):2231. doi: 10.3390/cells10092231.
2
Implications of Fibroblast Growth Factors (FGFs) in Cancer: From Prognostic to Therapeutic Applications.成纤维细胞生长因子(FGFs)在癌症中的意义:从预后到治疗应用。
Curr Drug Targets. 2019;20(8):852-870. doi: 10.2174/1389450120666190112145409.
3
The role of fibroblast growth factors and their receptors in prostate cancer.成纤维细胞生长因子及其受体在前列腺癌中的作用。
Endocr Relat Cancer. 2004 Dec;11(4):709-24. doi: 10.1677/erc.1.00535.
4
Molecular pathways: fibroblast growth factor signaling: a new therapeutic opportunity in cancer.分子途径:成纤维细胞生长因子信号转导:癌症治疗的新机会。
Clin Cancer Res. 2012 Apr 1;18(7):1855-62. doi: 10.1158/1078-0432.CCR-11-0699. Epub 2012 Mar 2.
5
Expression of fibroblast growth factor-8 and its cognate receptors, fibroblast growth factor receptor (FGFR)-3c and-4, in fetal bovine preantral follicles.成纤维细胞生长因子8及其同源受体,即成纤维细胞生长因子受体(FGFR)-3c和-4在胎牛腔前卵泡中的表达。
Mol Reprod Dev. 2005 Mar;70(3):255-61. doi: 10.1002/mrd.20205.
6
Fibroblast growth factors (FGFs) in cancer: FGF traps as a new therapeutic approach.成纤维细胞生长因子(FGFs)在癌症中的作用:FGF 陷阱作为一种新的治疗方法。
Pharmacol Ther. 2017 Nov;179:171-187. doi: 10.1016/j.pharmthera.2017.05.013. Epub 2017 May 28.
7
The potential of fibroblast growth factor/fibroblast growth factor receptor signaling as a therapeutic target in tumor angiogenesis.成纤维细胞生长因子/成纤维细胞生长因子受体信号传导作为肿瘤血管生成治疗靶点的潜力。
Expert Opin Ther Targets. 2015;19(10):1361-77. doi: 10.1517/14728222.2015.1062475. Epub 2015 Jun 30.
8
Fibroblast growth factor family aberrations in cancers: clinical and molecular characteristics.癌症中的成纤维细胞生长因子家族异常:临床和分子特征
Cell Cycle. 2015;14(13):2121-8. doi: 10.1080/15384101.2015.1041691. Epub 2015 May 7.
9
Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction.粗心的话会付出生命代价:成纤维细胞生长因子受体信号转导和通路功能障碍的后果。
Trends Cell Biol. 2015 Apr;25(4):221-33. doi: 10.1016/j.tcb.2014.11.003. Epub 2014 Nov 29.
10
Mechanisms of FGFR-mediated carcinogenesis.FGFR介导的致癌机制。
Biochim Biophys Acta. 2012 Apr;1823(4):850-60. doi: 10.1016/j.bbamcr.2012.01.004. Epub 2012 Jan 18.

引用本文的文献

1
Identification of miRNA/FGFR2 Axis in Well-Differentiated Gastroenteropancreatic Neuroendocrine Tumors.在高分化胃肠胰神经内分泌肿瘤中鉴定miRNA/FGFR2轴
Int J Mol Sci. 2025 Jul 26;26(15):7232. doi: 10.3390/ijms26157232.
2
Prominent fibroblast growth factor 21 with less abundant tumor-associated macrophages in hepatic mass of the conditional mgmt-deleted mice using LysM-Cre system.在使用LysM-Cre系统的条件性mgmt缺失小鼠的肝脏肿块中,成纤维细胞生长因子21显著,而肿瘤相关巨噬细胞较少。
Inflamm Res. 2025 Aug 9;74(1):109. doi: 10.1007/s00011-025-02077-6.
3
Therapies targeting triple-negative breast cancer: a perspective on anti-FGFR.针对三阴性乳腺癌的治疗:抗成纤维细胞生长因子受体的观点
Front Oncol. 2025 Mar 11;14:1415820. doi: 10.3389/fonc.2024.1415820. eCollection 2024.
4
The Complexity and Significance of Fibroblast Growth Factor (FGF) Signaling for FGF-Targeted Cancer Therapies.成纤维细胞生长因子(FGF)信号传导在FGF靶向癌症治疗中的复杂性及意义
Cancers (Basel). 2024 Dec 30;17(1):82. doi: 10.3390/cancers17010082.
5
Comprehensive analysis identifies endocrine fibroblast growth factors as promising prognostic markers for colorectal carcinoma.综合分析鉴定出内分泌成纤维细胞生长因子作为结直肠癌有前途的预后标志物。
Sci Rep. 2024 Nov 20;14(1):28754. doi: 10.1038/s41598-024-79341-y.
6
Molecular Mechanism for Malignant Progression of Gastric Cancer Within the Tumor Microenvironment.肿瘤微环境中胃癌恶性进展的分子机制。
Int J Mol Sci. 2024 Oct 31;25(21):11735. doi: 10.3390/ijms252111735.
7
STAT3 inhibitor Stattic Exhibits the Synergistic Effect with FGFRs Inhibitor Erdafitinib in FGFR1-positive Lung Squamous Cell Carcinoma.STAT3抑制剂Stattic与FGFRs抑制剂厄达替尼在FGFR1阳性肺鳞癌中表现出协同效应。
J Cancer. 2024 Aug 19;15(16):5415-5424. doi: 10.7150/jca.97477. eCollection 2024.
8
Targeting CERS6-AS1/FGFR1 axis as synthetic vulnerability to constrain stromal cells supported proliferation in Mantle cell lymphoma.靶向CERS6-AS1/FGFR1轴作为合成易损性以抑制套细胞淋巴瘤中基质细胞支持的增殖。
Leukemia. 2024 Oct;38(10):2196-2209. doi: 10.1038/s41375-024-02344-1. Epub 2024 Jul 13.
9
Comparative Analysis of Olive-Derived Phenolic Compounds' Pro-Melanogenesis Effects on B16F10 Cells and Epidermal Human Melanocytes.橄榄油衍生酚类化合物对B16F10细胞和人表皮黑素细胞促黑素生成作用的比较分析
Int J Mol Sci. 2024 Apr 19;25(8):4479. doi: 10.3390/ijms25084479.
10
The importance of protein domain mutations in cancer therapy.蛋白质结构域突变在癌症治疗中的重要性。
Heliyon. 2024 Mar 9;10(6):e27655. doi: 10.1016/j.heliyon.2024.e27655. eCollection 2024 Mar 30.

本文引用的文献

1
Cellular Mechanisms of FGF-Stimulated Tissue Repair.成纤维细胞生长因子刺激组织修复的细胞机制。
Cells. 2021 Jul 20;10(7):1830. doi: 10.3390/cells10071830.
2
Oncogenic FGFR Fusions Produce Centrosome and Cilia Defects by Ectopic Signaling.致癌性 FGFR 融合通过异位信号产生中心体和纤毛缺陷。
Cells. 2021 Jun 9;10(6):1445. doi: 10.3390/cells10061445.
3
Efficacy and Selectivity of FGF2-Saporin Cytosolically Delivered by PCI in Cells Overexpressing FGFR1.FGF2-丝氨酸蛋白酶融合蛋白通过 PCI 胞质递送在过表达 FGFR1 的细胞中的功效和选择性。
Cells. 2021 Jun 12;10(6):1476. doi: 10.3390/cells10061476.
4
Fibroblast Growth Factor Receptor (FGFR) Signaling in GIST and Soft Tissue Sarcomas.成纤维细胞生长因子受体(FGFR)信号在 GIST 和软组织肉瘤中的作用。
Cells. 2021 Jun 17;10(6):1533. doi: 10.3390/cells10061533.
5
Role of FGF15 in Hepatic Surgery in the Presence of Tumorigenesis: Dr. Jekyll or Mr. Hyde?成纤维细胞生长因子 15 在肿瘤发生时肝外科中的作用:是“化身博士”还是“两面人”?
Cells. 2021 Jun 7;10(6):1421. doi: 10.3390/cells10061421.
6
Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling.成纤维细胞生长因子受体(Fibroblast Growth Factor Receptor,FGFR)信号的负调控。
Cells. 2021 May 28;10(6):1342. doi: 10.3390/cells10061342.
7
Effects of FGFR Tyrosine Kinase Inhibition in OLN-93 Oligodendrocytes.成纤维细胞生长因子受体酪氨酸激酶抑制在 OLN-93 少突胶质细胞中的作用。
Cells. 2021 May 25;10(6):1318. doi: 10.3390/cells10061318.
8
Fibroblast Growth Factor Receptors (FGFRs) and Noncanonical Partners in Cancer Signaling.成纤维细胞生长因子受体(FGFRs)与癌症信号转导中的非经典伙伴。
Cells. 2021 May 14;10(5):1201. doi: 10.3390/cells10051201.
9
Targeting the Fibroblast Growth Factor Receptor (FGFR) Family in Lung Cancer.靶向肺癌中的成纤维细胞生长因子受体(FGFR)家族。
Cells. 2021 May 10;10(5):1154. doi: 10.3390/cells10051154.
10
FGF/FGFR Pathways in Multiple Sclerosis and in Its Disease Models.成纤维细胞生长因子/FGFR 通路在多发性硬化症及其疾病模型中的作用。
Cells. 2021 Apr 13;10(4):884. doi: 10.3390/cells10040884.

FGF-FGFR 信号系统在癌症发展和炎症中的作用。

Roles of the FGF-FGFR Signaling System in Cancer Development and Inflammation.

机构信息

Department of Molecular Cell Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Montebello, 0379 Oslo, Norway.

Center for Cancer Cell Reprogramming, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Montebello, 0379 Oslo, Norway.

出版信息

Cells. 2021 Aug 28;10(9):2231. doi: 10.3390/cells10092231.

DOI:10.3390/cells10092231
PMID:34571880
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8471549/
Abstract

For multi-cellular organisms to organize tissues, their cells must communicate with each other [...].

摘要

对于多细胞生物来说,要组织组织,它们的细胞必须相互沟通[...]。