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减肥手术与高血压

Bariatric Surgery and Hypertension.

作者信息

Climent Elisenda, Oliveras Anna, Pedro-Botet Juan, Goday Albert, Benaiges David

机构信息

Endocrinology Department, Hospital Universitari del Mar, 08003 Barcelona, Spain.

IMIM (Hospital del Mar Medical Research Institute), 08003 Barcelona, Spain.

出版信息

J Clin Med. 2021 Sep 7;10(18):4049. doi: 10.3390/jcm10184049.

DOI:10.3390/jcm10184049
PMID:34575161
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8467380/
Abstract

A clear pathogenetic association exists between obesity and arterial hypertension, becoming even more evident in subjects with severe obesity. Bariatric surgery has proved to be the most effective treatment for severe obesity, with its benefits going beyond weight loss. The present review aimed to determine the effects of bariatric surgery on arterial hypertension evident in short- and long-term follow-ups. Moreover, the differences between surgical techniques regarding hypertension remission are described as well as the possible pathophysiologic mechanisms involved. In addition, the effects of bariatric surgery beyond blood pressure normalization are also analyzed, including those on target organs and cardiovascular morbidity and mortality.

摘要

肥胖与动脉高血压之间存在明确的致病关联,在重度肥胖患者中这种关联更为明显。减肥手术已被证明是治疗重度肥胖最有效的方法,其益处不仅限于体重减轻。本综述旨在确定减肥手术在短期和长期随访中对明显的动脉高血压的影响。此外,还描述了手术技术在高血压缓解方面的差异以及可能涉及的病理生理机制。此外,还分析了减肥手术在血压正常化之外的影响,包括对靶器官以及心血管发病率和死亡率的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6571/8467380/c89474d20cbc/jcm-10-04049-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6571/8467380/c89474d20cbc/jcm-10-04049-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6571/8467380/c89474d20cbc/jcm-10-04049-g001.jpg

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本文引用的文献

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Effect of bariatric surgery on cardiac structure and function in obese patients: Role of the renin-angiotensin system.肥胖患者心脏结构和功能的减重手术影响:肾素-血管紧张素系统的作用。
J Clin Hypertens (Greenwich). 2021 Jan;23(1):181-192. doi: 10.1111/jch.14129. Epub 2020 Dec 17.
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Improvement in arterial stiffness (pOpmètre®) after bariatric surgery. Results from a prospective study.减重手术后动脉僵硬度(pOpmètre®)的改善。一项前瞻性研究的结果。
Ann Endocrinol (Paris). 2020 Feb;81(1):44-50. doi: 10.1016/j.ando.2020.01.002. Epub 2020 Feb 1.
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Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for 5-year hypertension remission in obese patients: a systematic review and meta-analysis.
代谢性减重手术后新发动脉高血压的发生率:一项为期8年的匹配对照前瞻性随访研究。
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Sleeve Gastrectomy in Patients with Type 2 Diabetes: Anthropometric and Cardiometabolic Improvements at 1, 3, 5, 7, and 9 years-Are the Initial Benefits Sustained?2型糖尿病患者的袖状胃切除术:1年、3年、5年、7年和9年时人体测量和心脏代谢指标的改善——最初的益处能否持续?
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Classification and Treatment Protocol of Post-bariatric Patients: An Anamnestic and Psychiatric Profiling.肥胖症手术后患者的分类与治疗方案:一项既往病历及精神状况分析
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