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减重手术:马来西亚一家专业中心的一年随访结果。

Bariatric surgeries: Outcome throughout an annum at a specialist center in Malaysia.

机构信息

Upper Gastrointestinal and Bariatric Surgery Department, Cengild Medical Centre, Bangsar South, Kuala Lumpur, Malaysia.

Community Medicine Department, University of Cyberjaya, Cyberjaya, Selangor, Malaysia.

出版信息

PLoS One. 2023 May 9;18(5):e0285196. doi: 10.1371/journal.pone.0285196. eCollection 2023.

DOI:10.1371/journal.pone.0285196
PMID:37159461
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10168565/
Abstract

INTRODUCTION

Malaysia has the highest number of obese and overweight individuals in South-east Asia. The 2019 National Health & Morbidity survey found 50.1% of Malaysians to be overweight or obese with 30.4% being overweight and 19.7% being obese. This has led to the high rise of the bariatric surgeries demand and needs within the nation.

AIM & OBJECTIVES: To assess the level of fasting blood sugar (FBS), systolic, diastolic blood pressure, stop BANG score for obstructive sleep apnoea (OSA) and BMI (Body Mass Index) for the patients before and after bariatric surgeries (sleeve/gastric bypass) for a one year follow up period.

MATERIAL & METHODS: The study was conducted among 1000 patients who underwent a single weight reduction surgery (sleeve/gastric bypass) by a single surgeon at the Cengild Medical Centre between January 2019 to January 2020. They were followed up for a one-year period through recording the parameters of fasting blood sugar (FBS), systolic, diastolic blood pressure, stop BANG score for obstructive sleep apnoea (OSA) and BMI (Body Mass Index). Study was conducted using universal sampling including all subjects visited the centre and a written consent was obtained from each participant. Descriptive statistics with mean was used and paired t-test was used for comparison and test the difference. The STOP-BANG acronym stands for: Snoring history, Tired during the day, Observed stop breathing while sleep, High blood pressure, BMI more than 35 kg/m2, Age more than 50 years, Neck circumference more than 40 cm and male Gender.

RESULTS

The mean age of patients was 38 years old. Mean FBS for the patients one month before the operation was 10.42 mmol/L and 5.84 three months post procedure. The systolic blood pressure one month before the operation and 3 months after was 139.81 mmHg and 123.79 mmHg, while diastolic blood pressure was 86.84 mmHg and 81.07 mmHg respectively. BMI was reduced from 39.69 to 27.99 after one year from the weight reduction operation. All the above parameters showed a significant reduction between one-month pre operation as compared to 3 months and 12 months post operation and that improved the health parameters of the patients significantly.

CONCLUSION

The weight reduction operations showed a significant reduction in the FBS, blood pressure, OSA scores and BMI at 3, 12 months after the operation These patients had better overall health after the significant reduction in these parameters.

摘要

简介

马来西亚是东南亚肥胖和超重人口最多的国家。2019 年全国健康和发病率调查发现,50.1%的马来西亚人超重或肥胖,其中 30.4%为超重,19.7%为肥胖。这导致了全国对减重手术需求的急剧增加。

目的和目标

评估 1000 名接受过单一减重手术(袖状胃切除术/胃旁路术)的患者在手术前后一年的空腹血糖(FBS)、收缩压、舒张压、阻塞性睡眠呼吸暂停(OSA)的停止 BANG 评分和 BMI(体重指数)的水平。

材料和方法

本研究于 2019 年 1 月至 2020 年 1 月期间,在森吉尔德医疗中心,由同一位外科医生对 1000 名患者进行了一项单一的减重手术(袖状胃切除术/胃旁路术)。通过记录空腹血糖(FBS)、收缩压、舒张压、阻塞性睡眠呼吸暂停(OSA)的停止 BANG 评分和 BMI(体重指数),对患者进行为期一年的随访。使用通用抽样法对所有接受中心就诊的患者进行研究,并获得每位参与者的书面同意。使用平均值进行描述性统计,使用配对 t 检验进行比较和检验差异。STOP-BANG 缩写代表:打鼾史、白天疲劳、睡眠时观察到呼吸暂停、高血压、BMI 超过 35kg/m2、年龄超过 50 岁、颈围超过 40cm 和男性。

结果

患者的平均年龄为 38 岁。手术前一个月患者的平均 FBS 为 10.42mmol/L,术后三个月为 5.84mmol/L。手术前一个月和术后三个月的收缩压分别为 139.81mmHg 和 123.79mmHg,舒张压分别为 86.84mmHg 和 81.07mmHg。BMI 从减重手术后一年的 39.69 降至 27.99。所有上述参数在手术前一个月与手术后三个月和 12 个月相比均有显著降低,这显著改善了患者的健康参数。

结论

减重手术后,患者的 FBS、血压、OSA 评分和 BMI 在术后 3 个月和 12 个月时均有显著降低。这些参数的显著降低使患者的整体健康状况得到改善。

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Obes Surg. 2022 Aug;32(8):2512-2524. doi: 10.1007/s11695-022-06124-7. Epub 2022 Jun 15.
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J Clin Med. 2021 Sep 7;10(18):4049. doi: 10.3390/jcm10184049.
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The Impact of Bariatric Surgery Versus Non-Surgical Treatment on Blood Pressure: Systematic Review and Meta-Analysis.减重手术与非手术治疗对血压影响的系统评价和荟萃分析。
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Effects of Bariatric Surgery in Obese Patients With Hypertension: The GATEWAY Randomized Trial (Gastric Bypass to Treat Obese Patients With Steady Hypertension).肥胖合并高血压患者行减重手术的效果:GATEWAY 随机试验(胃旁路术治疗持续高血压肥胖患者)。
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