Rindal Donald B, Mabry Patricia L
HealthPartners Institute, Minneapolis, MN 55425, USA.
J Pers Med. 2021 Aug 25;11(9):832. doi: 10.3390/jpm11090832.
Precision medicine is focused on serving the unique needs of individuals. Oral and oropharyngeal cancer risk assessment identifies individual risk factors while providing support to reduce risk. The objective is to examine potential current and future strategies to broadly implement evidence-based oral and oropharyngeal cancer risk assessment and screening in dental practices throughout the United States.
Feasible and effective oral cancer risk assessment and risk reduction strategies, ripe for implementation in dental practice, were identified in the published literature.
The Screening, Brief Intervention, Referral for Treatment (SBIRT) model is a feasible approach to assessing individual oral cancer risk and providing risk reducing interventions in the dental setting. HPV is a more recently identified risk factor that dentistry is well positioned to address. Evidence supporting the utilization of specific risk assessment tools and risk reduction strategies is summarized and future opportunities discussed.
Current knowledge of risk factors for oral and oropharyngeal cancers support the recommendation for dental providers to routinely assess all patients for risk factors, educate them about their personal level of cancer risk, and recommend actions to reduce relevant risk factors. Individuals ages 9-26 should be asked about their HPV vaccination status, educated about HPV and oropharyngeal cancer and receive a recommendation to get the HPV vaccination.
精准医疗专注于满足个体的独特需求。口腔和口咽癌风险评估可识别个体风险因素,同时为降低风险提供支持。目的是研究当前和未来可能的策略,以便在美国各地的牙科诊所广泛实施基于证据的口腔和口咽癌风险评估及筛查。
在已发表的文献中确定了在牙科实践中可行且有效的口腔癌风险评估和降低风险策略。
筛查、简短干预、转诊治疗(SBIRT)模式是在牙科环境中评估个体口腔癌风险并提供降低风险干预措施的可行方法。人乳头瘤病毒(HPV)是最近发现的一个风险因素,牙科领域有能力应对这一问题。总结了支持使用特定风险评估工具和降低风险策略的证据,并讨论了未来的机会。
目前关于口腔和口咽癌风险因素的知识支持建议牙科医疗人员常规评估所有患者的风险因素,向他们告知其个人癌症风险水平,并建议采取行动降低相关风险因素。应询问9至26岁个体的HPV疫苗接种状况,向他们介绍HPV和口咽癌的相关知识,并建议他们接种HPV疫苗。