Institute of Fundamental Medicine and Biology, Kazan Federal University, Kreml uramı 18, 420008 Kazan, Republic of Tatarstan, Russia.
Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov St., 8, 420088 Kazan, Republic of Tatarstan, Russia.
Int J Mol Sci. 2021 Sep 7;22(18):9670. doi: 10.3390/ijms22189670.
The problem of purifying domestic and hospital wastewater from pharmaceutical compounds is becoming more and more urgent every year, because of the continuous accumulation of chemical pollutants in the environment and the limited availability of freshwater resources. Clay adsorbents have been repeatedly proposed as adsorbents for treatment purposes, but natural clays are hydrophilic and can be inefficient for catching hydrophobic pharmaceuticals. In this paper, a comparison of adsorption properties of pristine montmorillonite (MMT) and montmorillonite modified with stearyl trimethyl ammonium (hydrophobic MMT-STA) towards carbamazepine, ibuprofen, and paracetamol pharmaceuticals was performed. The efficiency of adsorption was investigated under varying solution pH, temperature, contact time, initial concentration of pharmaceuticals, and adsorbate/adsorbent mass ratio. MMT-STA was better than pristine MMT at removing all the pharmaceuticals studied. The adsorption capacity of hydrophobic montmorillonite to pharmaceuticals decreased in the following order: carbamazepine (97%) > ibuprofen (95%) > paracetamol (63-67%). Adsorption isotherms were best described by Freundlich model. Within the pharmaceutical concentration range of 10-50 µg/mL, the most optimal mass ratio of adsorbates to adsorbents was 1:300, pH 6, and a temperature of 25 °C. Thus, MMT-STA could be used as an efficient adsorbent for deconta×ating water of carbamazepine, ibuprofen, and paracetamol.
从药物化合物中净化家庭和医院废水的问题每年都变得越来越紧迫，这是由于环境中化学污染物的不断积累和淡水资源的有限可用性。粘土吸附剂已被反复提出作为处理目的的吸附剂，但天然粘土是亲水性的，对于捕获疏水性药物可能效率不高。在本文中，对原始蒙脱石（MMT）和用硬脂基三甲基铵（疏水性 MMT-STA）改性的蒙脱石对卡马西平、布洛芬和扑热息痛药物的吸附性能进行了比较。研究了在不同溶液 pH 值、温度、接触时间、药物初始浓度和吸附剂/吸附剂质量比下的吸附效率。在去除所有研究药物方面，MMT-STA 优于原始 MMT。疏水性蒙脱石对药物的吸附容量按以下顺序降低：卡马西平（97%）>布洛芬（95%）>扑热息痛（63-67%）。吸附等温线最好由 Freundlich 模型描述。在药物浓度范围为 10-50 µg/mL 内，最优选的吸附剂与吸附剂的质量比为 1:300、pH 值为 6 和温度为 25°C。因此，MMT-STA 可用作去除卡马西平、布洛芬和扑热息痛水中污染物的有效吸附剂。
